{"id":"W3034982030","doi":"10.1136/annrheumdis-2020-eular.1972","title":"AB0301 SARILUMAB AS MONOTHERAPY OR IN COMBINATION WITH CONVENTIONAL SYNTHETIC DMARDS IN PATIENTS WITH RHEUMATOID ARTHRITIS: 12-WEEK TREATMENT RESULTS FROM A MULTICENTER, OPEN-LABEL, PROSPECTIVE, SINGLE-ARM OBSERVATIONAL STUDY","year":2020,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Medicine; Interim analysis; Observational study; Clinical endpoint; Adverse effect; Internal medicine; Population; Rheumatoid arthritis; Clinical trial; Randomized controlled trial; Physical therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00492341,0.002070248,0.004049921,0.0006182789,0.00073231,0.001762975,0.001169118,0.002184717,0.00189569],"category_scores_gemma":[0.003795337,0.001135755,0.003679568,0.001130904,0.001155081,0.001710987,0.0006224259,0.002722173,0.000787747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006851974,"about_ca_system_score_gemma":0.0009205004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001549724,"about_ca_topic_score_gemma":0.001816049,"domain_scores_codex":[0.9968394,0.001657,0.0002887833,0.0005995798,0.0003033187,0.0003120071],"domain_scores_gemma":[0.9944285,0.001643584,0.001926944,0.0006383318,0.0004499592,0.0009126867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8509335,0.009745315,0.1090535,0.0006815745,0.007175059,0.0001818866,0.0002312942,0.0004597019,0.005490194,0.00004908638,0.0007166151,0.0152822],"study_design_scores_gemma":[0.3635921,0.164001,0.4561942,0.000138057,0.01059702,0.0005357662,0.0004129579,0.001830639,0.001148247,0.0001843543,0.001171486,0.0001940296],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970773,0.001726954,0.0001385582,0.00006787775,0.00004993163,0.0001411496,0.000509374,0.00001410861,0.0002747589],"genre_scores_gemma":[0.9965495,0.0007574395,0.0003842489,0.0002911923,0.0001855342,0.0002052058,0.001263594,0.000009847498,0.0003534217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00492341,"threshold_uncertainty_score":0.02603775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1128154960863676,"score_gpt":0.3311556429888915,"score_spread":0.2183401469025239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}