{"id":"W3035079538","doi":"10.4049/jimmunol.1900687","title":"Cutting Edge: Intestinal Mucus Limits the Clonal Deletion of Developing T Cells Specific for an Oral Antigen","year":2020,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Canada","keywords":"Mucus; Mucin; Immune system; Mucin 2; Biology; Immunology; CD8; Antigen presentation; Antigen; Intestinal epithelium; T cell; Epithelium; Cell biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000174116,0.000290749,0.000243597,0.0001584858,0.0001022629,0.000452174,0.0003145522,0.0005171011,0.001655837],"category_scores_gemma":[0.0002170068,0.0001373436,0.0001574432,0.00006141565,0.0002579909,0.0002776752,0.0002701521,0.0006390733,0.0003553712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001721597,"about_ca_system_score_gemma":0.0002130096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002386557,"about_ca_topic_score_gemma":0.0004089918,"domain_scores_codex":[0.9997709,0.00003448995,0.00001676153,0.00003784236,0.00007892608,0.00006097649],"domain_scores_gemma":[0.9998013,0.0000315968,0.00005670039,0.0000232231,0.00002036274,0.00006677391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001047658,0.00001506033,0.0002489954,0.00003363198,0.000001990639,0.00002208403,0.00001043436,0.00001556178,0.997957,0.00008635575,0.00002834074,0.001475679],"study_design_scores_gemma":[0.00003171121,0.001063312,0.006526482,0.00002872617,0.00002736881,0.0003672265,0.00005780852,0.0007319877,0.9871466,0.0001084359,0.003905852,0.000004534093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949158,0.001710034,0.001625303,0.0001518602,0.00003442832,0.00001581884,0.0001231233,0.0000655219,0.001358178],"genre_scores_gemma":[0.9960667,0.000472262,0.001186026,0.0001081621,0.00001781278,0.00001338338,0.0001105095,0.00002108539,0.002004142],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001655837,"threshold_uncertainty_score":0.005539358,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05746491658964104,"score_gpt":0.3078250290086211,"score_spread":0.2503601124189801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}