{"id":"W3035152834","doi":"10.1016/j.autrev.2020.102583","title":"Autoantibodies to stratify systemic sclerosis patients into clinically actionable subsets","year":2020,"lang":"en","type":"review","venue":"Autoimmunity Reviews","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; McGill University; Jewish General Hospital","funders":"","keywords":"Medicine; Autoantibody; Disease; Etiology; Scleroderma (fungus); Multisystem disease; Fibrosis; Pathology; Interstitial lung disease; Systemic disease; Immunology; Lung; Internal medicine; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001381486,0.00108188,0.007446447,0.0003143362,0.0003829581,0.0001404519,0.0008079942,0.0008830207,0.0003461802],"category_scores_gemma":[0.002396408,0.0007467677,0.002402509,0.001263996,0.0001183589,0.0001535691,0.0003977735,0.001473838,0.007313205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006447961,"about_ca_system_score_gemma":0.001058404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001482506,"about_ca_topic_score_gemma":0.000003606329,"domain_scores_codex":[0.9919278,0.001530736,0.004294823,0.0009857821,0.0006784822,0.0005823971],"domain_scores_gemma":[0.9948137,0.0004274214,0.001813014,0.001831852,0.0003570362,0.0007569708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002480003,0.0003401795,0.0001361768,0.0614365,0.0005419043,0.00000933516,0.0002113679,1.828211e-7,0.00001127702,0.00001494772,0.01592515,0.9213482],"study_design_scores_gemma":[0.000420691,0.0002834978,0.0004599745,0.2733363,0.003290813,0.00004436078,0.00004481144,0.000001663213,4.614106e-7,0.000002687794,0.7216254,0.0004893575],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001369717,0.9900376,0.00001230297,0.0001392102,0.001076091,0.006989188,0.0001135675,0.0002856674,0.001209452],"genre_scores_gemma":[0.0002271172,0.9954662,0.0004675085,0.0006741502,0.000314149,0.0007865641,0.001033773,0.0001590474,0.0008714884],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9208588,"threshold_uncertainty_score":0.9994983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1351874159081102,"score_gpt":0.3863147603244939,"score_spread":0.2511273444163837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}