{"id":"W3035367631","doi":"10.1136/annrheumdis-2020-eular.2553","title":"THU0377 IMPACT OF FILGOTINIB ON STRUCTURAL LESIONS IN THE SACROILIAC JOINTS AT 12 WEEKS IN PATIENTS WITH ACTIVE AXIAL SPONDYLOARTHRITIS: MAGNETIC RESONANCE IMAGING DATA FROM THE DOUBLE-BLIND, RANDOMIZED TORTUGA TRIAL","year":2020,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Biogen; Gilead Sciences; Galápagos; Amgen","keywords":"Medicine; Magnetic resonance imaging; Ankylosing spondylitis; Post-hoc analysis; Randomization; Placebo; Internal medicine; Sacroiliac joint; Randomized controlled trial; Nuclear medicine; Physical therapy; Surgery; Radiology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001315479,0.001667958,0.003143628,0.0002978196,0.0004270629,0.001119385,0.0007666628,0.001629609,0.005247417],"category_scores_gemma":[0.001353165,0.0005414238,0.002344596,0.0003658433,0.00119191,0.001045805,0.000323144,0.002864266,0.0009401329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005824982,"about_ca_system_score_gemma":0.0007888888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001936221,"about_ca_topic_score_gemma":0.004438228,"domain_scores_codex":[0.999498,0.0002670429,0.00002854434,0.00007347995,0.00003422059,0.00009864195],"domain_scores_gemma":[0.9993172,0.0002089675,0.0001543995,0.00005909216,0.00005533772,0.0002049703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9739556,0.002418746,0.0005531246,0.0008684762,0.001867819,0.00005338215,0.00005232155,0.0003494524,0.002719015,0.0001077158,0.001076834,0.01597754],"study_design_scores_gemma":[0.9321444,0.0605799,0.004429146,0.00007329089,0.001107939,0.0000658303,0.00005985486,0.0003536059,0.0003833943,0.0001208459,0.0006566276,0.00002515034],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98401,0.01050123,0.0002812344,0.0007286126,0.0005611788,0.0004443398,0.0008785561,0.0001282652,0.002466478],"genre_scores_gemma":[0.9903514,0.00379593,0.0004983243,0.0007594451,0.0003827862,0.0004863655,0.001035249,0.00001901204,0.00267156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005247417,"threshold_uncertainty_score":0.01755434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06945419231117657,"score_gpt":0.3318452717819742,"score_spread":0.2623910794707977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}