{"id":"W3035377921","doi":"10.1111/jpi.12674","title":"Melatonin recovers sleep phase delayed by MK‐801 through the melatonin MT<sub>2</sub> receptor‐ Ca<sup>2+</sup>‐CaMKII‐CREB pathway in the ventrolateral preoptic nucleus","year":2020,"lang":"en","type":"article","venue":"Journal of Pineal Research","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Natural Science Foundation of China","keywords":"Melatonin; NMDA receptor; Internal medicine; Suprachiasmatic nucleus; Melatonin receptor; Endocrinology; CREB; Receptor; Neuroscience; Chemistry; Biology; Hypothalamus; Medicine; Biochemistry; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.004111546,0.0004437691,0.0006678014,0.0002908361,0.0007050182,0.0004878861,0.001885674,0.0002919397,0.0002827183],"category_scores_gemma":[0.00339374,0.0002849364,0.0004405161,0.001761745,0.0005664296,0.0009804141,0.0002838708,0.003941391,0.0004506571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004482731,"about_ca_system_score_gemma":0.0006920383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000878158,"about_ca_topic_score_gemma":0.00001335455,"domain_scores_codex":[0.9909294,0.002767217,0.001295502,0.0007156323,0.002761226,0.00153106],"domain_scores_gemma":[0.9958625,0.002065968,0.0004956344,0.000659782,0.0003116991,0.0006043889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004504718,0.001157542,0.0002420319,0.0000934758,0.000175198,0.001867877,0.05519387,0.005955566,0.8385628,0.004121497,0.07400772,0.01411763],"study_design_scores_gemma":[0.008938509,0.005026843,0.0001730766,0.0002245865,0.00007157592,0.001208491,0.006038005,0.04973323,0.7011419,0.000607766,0.2261394,0.0006966495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9719259,0.001902389,0.0001628307,0.02335351,0.0003197403,0.0009489674,0.0001555403,0.00003053321,0.001200622],"genre_scores_gemma":[0.9949712,0.001405729,0.0001034523,0.002471878,0.0007736777,0.00004164753,0.000009004663,0.00008385551,0.0001395809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1521316,"threshold_uncertainty_score":0.9999603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05664489499315523,"score_gpt":0.3279367975758863,"score_spread":0.2712919025827311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}