{"id":"W3035377921","doi":"10.1111/jpi.12674","title":"Melatonin recovers sleep phase delayed by MK‐801 through the melatonin MT2 receptor‐ Ca2+‐CaMKII‐CREB pathway in the ventrolateral preoptic nucleus","year":2020,"lang":"en","type":"article","venue":"Journal of Pineal Research","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Natural Science Foundation of China","keywords":"Melatonin; NMDA receptor; Internal medicine; Suprachiasmatic nucleus; Melatonin receptor; Endocrinology; CREB; Receptor; Neuroscience; Chemistry; Biology; Hypothalamus; Medicine; Biochemistry; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006881883,0.0003417768,0.0002607405,0.0001880148,0.0001093803,0.0001427997,0.0001720333,0.0002001018,0.001334991],"category_scores_gemma":[0.0000821646,0.0001246724,0.0002648071,0.00006410474,0.0002333999,0.0002299121,0.0001417954,0.0006129196,0.0002934151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002315131,"about_ca_system_score_gemma":0.0002619285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009582384,"about_ca_topic_score_gemma":0.001967967,"domain_scores_codex":[0.9999504,0.000004668412,0.000005983456,0.00001040164,0.00001143593,0.00001705668],"domain_scores_gemma":[0.9999431,0.000002983983,0.00002333101,0.000005544645,0.000005437962,0.00001951518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004550462,0.00004267133,0.00009652296,0.00002872201,0.000004734305,0.00004153088,0.00001161183,0.00002520994,0.998378,0.00003355353,0.00003532679,0.0008471341],"study_design_scores_gemma":[0.0001602477,0.001862715,0.01021188,0.00001057785,0.00002991017,0.0001514799,0.00006389342,0.001090558,0.9850662,0.00008887829,0.001256504,0.000007160362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971083,0.0006333159,0.001144306,0.00008907487,0.00005692403,0.00002535208,0.000251502,0.0001321852,0.0005590232],"genre_scores_gemma":[0.9955318,0.000474383,0.0008329306,0.00006703791,0.00001531007,0.00007065896,0.0002711204,0.00003218837,0.002704554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001334991,"threshold_uncertainty_score":0.004465997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05664489499315523,"score_gpt":0.3279367975758863,"score_spread":0.2712919025827311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}