{"id":"W3035385671","doi":"10.1016/j.isci.2020.101259","title":"Selective Quadruple C(sp3)-F Functionalization of Polyfluoroalkyl Ketones","year":2020,"lang":"en","type":"article","venue":"iScience","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Education and Child Care","funders":"Nanjing Tech University; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"Chemistry; Surface modification; Combinatorial chemistry; Benzofuran; Catalysis; Heteronuclear molecule; Furan; Context (archaeology); Nucleophile; Amination; Organic chemistry; Nuclear magnetic resonance spectroscopy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001025888,0.0002992809,0.00009241972,0.000131711,0.0001366231,0.0001176561,0.0002022656,0.0002616786,0.003224902],"category_scores_gemma":[0.0001562902,0.00007384033,0.0001064221,0.0001075108,0.0001433961,0.0003291194,0.0001980537,0.0004013964,0.0005227804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001737554,"about_ca_system_score_gemma":0.0001634826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000841977,"about_ca_topic_score_gemma":0.001864155,"domain_scores_codex":[0.9999328,0.000006249042,0.000002977766,0.00001541325,0.00001070196,0.00003181896],"domain_scores_gemma":[0.9999379,0.00001576175,0.00001500591,0.000008685417,0.000009781103,0.0000128884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002219813,0.00003456555,0.0001820729,0.0001890419,0.00000783636,0.0002230723,0.00006189226,0.0005235283,0.9780531,0.002105394,0.001056717,0.01734082],"study_design_scores_gemma":[0.00001107369,0.0002291646,0.0008131056,0.00001046258,0.000004556183,0.0002539037,0.00001915417,0.001552009,0.9915911,0.0001821338,0.005318558,0.00001465568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9622065,0.001848606,0.02271682,0.0001865971,0.0001265837,0.00005432413,0.0005270457,0.0002764393,0.01205701],"genre_scores_gemma":[0.9924222,0.0005625162,0.003648179,0.00004811678,0.000009887824,0.00002275105,0.0001469488,0.00001639238,0.003123058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003224902,"threshold_uncertainty_score":0.01078838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1046097250630918,"score_gpt":0.4042692713457887,"score_spread":0.2996595462826969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}