{"id":"W3035518313","doi":"10.29052/jehsr.v8.i2.2020.86-108","title":"Epigenetic Modifications lead towards Neurodegeneration","year":2020,"lang":"en","type":"article","venue":"INTERNATIONAL JOURNAL OF ENDORSING HEALTH SCIENCE RESEARCH (IJEHSR)","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Health Canada","funders":"Cardiff University","keywords":"Neurodegeneration; Lead (geology); Epigenetics; Neuroscience; Epigenesis; Biology; Medicine; Disease; Genetics; DNA methylation; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01417163,0.0008860611,0.001926534,0.002573706,0.0003815661,0.002531315,0.001175619,0.002239672,0.008266799],"category_scores_gemma":[0.03625344,0.0004475605,0.003953777,0.002336617,0.001582741,0.00228753,0.001370791,0.001488506,0.0005968505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001785566,"about_ca_system_score_gemma":0.004862489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002176632,"about_ca_topic_score_gemma":0.003447097,"domain_scores_codex":[0.9849833,0.008020245,0.002842371,0.001324653,0.002562368,0.0002671149],"domain_scores_gemma":[0.9586549,0.03041216,0.00761121,0.000671261,0.002447925,0.0002026076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001365126,0.00009995557,0.01169549,0.600503,0.01954131,0.0006000423,0.001244292,0.001176649,0.001312429,0.01550564,0.02377334,0.3231827],"study_design_scores_gemma":[0.0008744713,0.001364345,0.04496876,0.5561483,0.04942791,0.002722122,0.001743041,0.001256851,0.004993531,0.03247082,0.3038187,0.000211187],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.003443001,0.981544,0.001774337,0.007990289,0.001056354,0.0003337798,0.0007516677,0.00003309059,0.003073395],"genre_scores_gemma":[0.08939385,0.8913779,0.005067818,0.009361736,0.001495642,0.0008068497,0.0007051039,0.0000201651,0.001770955],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01417163,"threshold_uncertainty_score":0.07494766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1980428991155803,"score_gpt":0.4821682603593424,"score_spread":0.2841253612437621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}