{"id":"W3035620538","doi":"10.1182/blood.v130.suppl_1.1070.1070","title":"Evaluation of Plasma-Derived FVII Efficacy for the Treatment of Bleeding in a Murine Model of Hemophilia a","year":2017,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Impact","funders":"","keywords":"Hemostasis; Titer; Medicine; Antibody; Factor IX; Coagulation; Saline; Recombinant factor VIIa; Bleeding time; Recombinant DNA; Factor VII; Pharmacology; Coagulopathy; Immunology; Antibody titer; Internal medicine; Chemistry; Platelet; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005424382,0.0006985735,0.0005001046,0.0007312448,0.0002285409,0.0004608826,0.0004468328,0.0007363475,0.001367129],"category_scores_gemma":[0.0001739625,0.0001834523,0.0004417123,0.0002821126,0.0003812019,0.0003337446,0.0001447033,0.001540051,0.0003002635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003341948,"about_ca_system_score_gemma":0.0003047283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003370389,"about_ca_topic_score_gemma":0.0005446123,"domain_scores_codex":[0.9996597,0.00007392949,0.00003199122,0.00006164511,0.0001067126,0.00006616527],"domain_scores_gemma":[0.9996573,0.00004621263,0.0001067139,0.00003300643,0.00004079962,0.0001161359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001106415,0.001207395,0.0001747354,0.0001175645,0.00002183327,0.00005543351,0.00001940212,0.0002397731,0.9929754,0.0001518213,0.0001556097,0.003774657],"study_design_scores_gemma":[0.0004108679,0.02752894,0.002724987,0.00002740098,0.0000951021,0.0003468848,0.00002537867,0.001325053,0.9639767,0.00006792559,0.003457078,0.00001365388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886112,0.003003141,0.004928193,0.0002306912,0.0001014036,0.0003639787,0.001067369,0.0001820298,0.001512056],"genre_scores_gemma":[0.9839469,0.002852601,0.007934605,0.0001270467,0.00007018966,0.0004445783,0.001480387,0.00004687882,0.003096817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001367129,"threshold_uncertainty_score":0.004573464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1463728233219882,"score_gpt":0.3859753216586265,"score_spread":0.2396024983366384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}