{"id":"W3035776121","doi":"10.1111/imr.12890","title":"T cell help to B cells: Cognate and atypical interactions in peripheral and intestinal lymphoid tissues","year":2020,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Human Frontier Science Program","keywords":"Germinal center; Biology; B cell; Antibody; Somatic hypermutation; Immunology; Cognate; Immune system; B-cell receptor; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004547075,0.0009847565,0.003951272,0.0002748265,0.0002074739,0.00007741895,0.0006568323,0.0008027377,0.001041022],"category_scores_gemma":[0.0005222567,0.0006910294,0.0004353692,0.0004920654,0.0006374808,0.0001067189,0.001031511,0.001993412,0.003344108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001797081,"about_ca_system_score_gemma":0.0001141672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006444297,"about_ca_topic_score_gemma":0.00002528043,"domain_scores_codex":[0.9946138,0.001628219,0.001637148,0.001262387,0.00004844066,0.0008100256],"domain_scores_gemma":[0.9981253,0.0007136929,0.0004865844,0.0005102858,0.00004919433,0.0001149425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001679992,0.0002220829,0.00001211295,0.001866225,0.0001033929,0.00008372989,0.0001433253,3.83332e-8,0.028767,0.0000967134,0.001140826,0.9673966],"study_design_scores_gemma":[0.0006584534,0.0006321198,0.00001427838,0.005129849,0.000314367,0.001178896,0.00007217715,5.918714e-7,0.0005426011,0.00003743239,0.9907204,0.0006988539],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000669245,0.9957231,0.00003200617,0.0002283218,0.0008529781,0.00178072,0.00004233009,0.0001104395,0.0005608245],"genre_scores_gemma":[0.000579539,0.9951119,0.0005058188,0.0003082684,0.00006810552,0.0004463859,0.0001384463,0.00005581751,0.002785696],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9895796,"threshold_uncertainty_score":0.9998721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05947548315837826,"score_gpt":0.3279546735487396,"score_spread":0.2684791903903614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}