{"id":"W3035991124","doi":"10.1080/22221751.2020.1787108","title":"In vivo expressed biologics for infectious disease prophylaxis: rapid delivery of DNA-based antiviral antibodies","year":2020,"lang":"en","type":"article","venue":"Emerging Microbes & Infections","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"","keywords":"Pandemic; Outbreak; Medicine; Infectious disease (medical specialty); Virology; Disease; Monoclonal antibody; Coronavirus disease 2019 (COVID-19); Immunology; Intensive care medicine; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004499603,0.0005233031,0.0002920061,0.0003383644,0.0001358742,0.000766879,0.0003796488,0.0008561119,0.002034336],"category_scores_gemma":[0.0003603093,0.0002511944,0.0003404908,0.000155492,0.0002736249,0.0006238576,0.0003231865,0.001325868,0.001361271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005659773,"about_ca_system_score_gemma":0.0002421338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003654638,"about_ca_topic_score_gemma":0.0003793549,"domain_scores_codex":[0.9996969,0.00006918056,0.00001295706,0.00007032751,0.0001056708,0.00004494549],"domain_scores_gemma":[0.9999133,0.00001824776,0.00002526894,0.0000068854,0.00001805752,0.00001823471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001336492,0.0001029087,0.00007565667,0.0002099307,0.00001642909,0.00008549175,0.00003420183,0.000530966,0.971982,0.001497822,0.001338709,0.02399229],"study_design_scores_gemma":[0.00008966343,0.001294558,0.0004022953,0.00004779692,0.00004336254,0.0005010567,0.00002317004,0.004387973,0.9453312,0.0005197268,0.04733735,0.00002182419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4373411,0.1256465,0.3817476,0.006030726,0.00336757,0.001135406,0.002173955,0.002775223,0.03978195],"genre_scores_gemma":[0.8643749,0.03219444,0.07955629,0.001720711,0.0003632666,0.0004176582,0.001140341,0.000170794,0.02006168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002034336,"threshold_uncertainty_score":0.006805539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02581644372144032,"score_gpt":0.3017978485485825,"score_spread":0.2759814048271422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}