{"id":"W3036001456","doi":"10.1097/ju.0000000000001199","title":"Five-Factor Prognostic Model for Survival of Post-Platinum Patients with Metastatic Urothelial Carcinoma Receiving PD-L1 Inhibitors","year":2020,"lang":"en","type":"article","venue":"The Journal of Urology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Cancer Institute","keywords":"Medicine; Durvalumab; Atezolizumab; Oncology; Metastatic Urothelial Carcinoma; Proportional hazards model; Internal medicine; Avelumab; Cancer; Bladder cancer; Immunotherapy; Urothelial carcinoma; Nivolumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004944765,0.001424185,0.001330499,0.00179692,0.0004395778,0.001228678,0.001442119,0.0009519305,0.002969839],"category_scores_gemma":[0.006846148,0.0004046637,0.002238392,0.0006803449,0.0004144149,0.0004571806,0.0006241371,0.001610143,0.000691305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001212626,"about_ca_system_score_gemma":0.001503496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0109001,"about_ca_topic_score_gemma":0.004413225,"domain_scores_codex":[0.9987999,0.0006381984,0.00006319152,0.0002290221,0.0001186382,0.0001510614],"domain_scores_gemma":[0.9954802,0.003222995,0.0004197978,0.0001808677,0.0004692121,0.0002269113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","study_design_scores_codex":[0.002028607,0.000549162,0.3136503,0.00009027289,0.001148692,0.0005039333,0.0001516232,0.6463861,0.0009150383,0.001025535,0.003049759,0.03050093],"study_design_scores_gemma":[0.00005759268,0.0002040759,0.01801646,0.00001899749,0.0001470441,0.0001189914,0.00002801628,0.9800754,0.0001344921,0.0008350516,0.0003457463,0.0000181718],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9026261,0.001114025,0.08837518,0.00169823,0.0001529453,0.0002323452,0.00377754,0.0006445663,0.001379082],"genre_scores_gemma":[0.9910775,0.0001441617,0.005341742,0.0000640166,0.00003484581,0.0001159912,0.002240994,0.00002033883,0.0009604285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0109001,"threshold_uncertainty_score":0.02615076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02737818199017169,"score_gpt":0.2623216373181284,"score_spread":0.2349434553279567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}