{"id":"W3036100757","doi":"10.1016/j.jhep.2020.06.011","title":"Similar risk of hepatocellular carcinoma during long-term entecavir or tenofovir therapy in Caucasian patients with chronic hepatitis B","year":2020,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"Merck Sharp and Dohme; Gilead Sciences; Roche; Novartis; AbbVie; Merck; GlaxoSmithKline; Janssen Pharmaceuticals; Bayer; Bristol-Myers Squibb","keywords":"Medicine; Hepatocellular carcinoma; Entecavir; Cirrhosis; Internal medicine; Gastroenterology; Hazard ratio; Incidence (geometry); HBsAg; Hepatitis B; Cumulative incidence; Proportional hazards model; Liver transplantation; Cohort; Hepatitis B virus; Transplantation; Immunology; Lamivudine; Confidence interval; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002057068,0.0003313408,0.001363171,0.0003395124,0.00008125033,0.000008495754,0.0002332414,0.0001726945,0.0002040998],"category_scores_gemma":[0.0002440822,0.0002267381,0.0002136907,0.0004190161,0.0002270229,0.0001657161,0.00008496546,0.0006651026,0.00000933005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003392425,"about_ca_system_score_gemma":0.0005379523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001283756,"about_ca_topic_score_gemma":0.004592069,"domain_scores_codex":[0.9972552,0.0002647529,0.001162969,0.00030761,0.0005242383,0.0004852498],"domain_scores_gemma":[0.9979168,0.000120057,0.0009734079,0.0002818379,0.0004332555,0.000274659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003281687,0.0004169584,0.9869649,0.0003072211,0.0004548804,0.004059379,0.001221817,0.000008909308,0.0009644459,0.000001744367,0.00007014855,0.00224791],"study_design_scores_gemma":[0.009172239,0.007003547,0.9759246,0.0002714891,0.0001904441,0.0004314803,0.00002282209,0.0001573198,0.006424136,0.000005046395,0.0001932678,0.0002036182],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955295,0.002606715,0.00006282095,0.0009879713,0.0001532076,0.0005742389,0.00003258557,0.00001706541,0.0000359139],"genre_scores_gemma":[0.9944801,0.004637762,0.0002916954,0.0003198006,0.000190233,0.00001210376,0.000006363843,0.00005001023,0.00001195193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01104031,"threshold_uncertainty_score":0.9246114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01909323869572797,"score_gpt":0.250120275602785,"score_spread":0.2310270369070571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}