{"id":"W3036142390","doi":"10.1126/science.abb4129","title":"Direct reversible decarboxylation from stable organic acids in dimethylformamide solution","year":2020,"lang":"en","type":"article","venue":"Science","topic":"Chemical Reactions and Isotopes","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Killam Trusts; University of Alberta","keywords":"Chemistry; Decarboxylation; Dimethylformamide; Ring (chemistry); Alcohol; Organic chemistry; Carbon dioxide; Catalysis; Carbon fibers; Medicinal chemistry; Photochemistry; Solvent","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004397329,0.00007884977,0.0001081626,0.00006390824,0.000185506,0.00002533181,0.0002360816,0.00008664598,0.0009788541],"category_scores_gemma":[0.0003833582,0.0000756212,0.00002478438,0.001026312,0.0002066365,0.0004609504,0.00009915527,0.0003024642,0.0001805936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001522164,"about_ca_system_score_gemma":0.0001561432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001029225,"about_ca_topic_score_gemma":0.00004201184,"domain_scores_codex":[0.9990796,0.00005037804,0.0001587301,0.0002732669,0.0001557278,0.0002823253],"domain_scores_gemma":[0.9995016,0.0001351466,0.00004874411,0.00009489974,0.00004727758,0.0001723674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004048663,0.00003436381,0.02356658,0.000003389438,0.000003758923,0.000001941845,0.0004272925,0.0001387791,0.9726002,0.00005360343,0.0003508099,0.002778749],"study_design_scores_gemma":[0.0004546368,0.00003573931,0.018945,0.000006890852,0.00001575612,6.582496e-7,0.0001007352,0.01781904,0.8955576,0.0003021098,0.06663482,0.0001270035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877597,0.000258757,0.0004604913,0.001222048,0.000350465,0.0001250131,0.0000139658,0.00005734995,0.009752199],"genre_scores_gemma":[0.9981636,0.0001254193,0.0004836186,0.000981556,0.00008335915,0.00000601295,0.000008667616,0.000004724172,0.0001429978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07704263,"threshold_uncertainty_score":0.9999344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1035966237679618,"score_gpt":0.3961645291862798,"score_spread":0.2925679054183181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}