{"id":"W3036187761","doi":"10.1093/nar/gkaa518","title":"IncC conjugative plasmids and SXT/R391 elements repair double-strand breaks caused by CRISPR–Cas during conjugation","year":2020,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Université de Sherbrooke; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Simon Fraser University","keywords":"Biology; CRISPR; Plasmid; Genetics; Genome editing; DNA; Computational biology; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001743994,0.0005896689,0.0003758132,0.0004431982,0.0001850937,0.0003449199,0.0003795144,0.0003931235,0.001484401],"category_scores_gemma":[0.0001976539,0.0002248387,0.00052411,0.0003048242,0.0003597404,0.0001782716,0.0005697822,0.0007378901,0.0005567688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003648701,"about_ca_system_score_gemma":0.0002964188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004629055,"about_ca_topic_score_gemma":0.0005601032,"domain_scores_codex":[0.9995782,0.00004918854,0.00003958159,0.000108058,0.0001539754,0.000071006],"domain_scores_gemma":[0.999762,0.00003462067,0.0001000555,0.00005307761,0.00001527373,0.00003496372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003238557,0.00003511011,0.0006309983,0.00002740997,0.000007728217,0.00007084981,0.00001660918,0.00009870389,0.9964089,0.0001787303,0.00003460123,0.002458001],"study_design_scores_gemma":[0.000009561039,0.0001799079,0.005213378,0.000005978611,0.00001554096,0.0006795225,0.00002548414,0.0009719058,0.9907387,0.00006203237,0.002090884,0.000006933941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838617,0.0005090243,0.01261878,0.00009362126,0.00002526751,0.00006826972,0.000464939,0.000303792,0.002054554],"genre_scores_gemma":[0.9830338,0.000196044,0.01098068,0.00005373542,0.000007234564,0.00005657623,0.001360212,0.00006028312,0.004251256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001484401,"threshold_uncertainty_score":0.004965782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02737472838029147,"score_gpt":0.3524631148385412,"score_spread":0.3250883864582497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}