{"id":"W3036187761","doi":"10.1093/nar/gkaa518","title":"IncC conjugative plasmids and SXT/R391 elements repair double-strand breaks caused by CRISPR–Cas during conjugation","year":2020,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Université de Sherbrooke; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Simon Fraser University","keywords":"Biology; CRISPR; Plasmid; Genetics; Genome editing; DNA; Computational biology; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003887232,0.0001991268,0.0001922071,0.00006674671,0.0002282088,0.00007037274,0.0001999118,0.0001951764,0.00007756861],"category_scores_gemma":[0.0001304776,0.000206948,0.00006123555,0.0002052511,0.0002011169,0.00001213035,0.0002711456,0.0003415651,0.00002883887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003420571,"about_ca_system_score_gemma":0.00005856587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000043957,"about_ca_topic_score_gemma":0.0000201007,"domain_scores_codex":[0.9981161,0.00009707562,0.0002922209,0.0005775744,0.0004219857,0.0004950658],"domain_scores_gemma":[0.9991754,0.00003172064,0.00004154139,0.0002700331,0.0001837238,0.0002975601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004520025,0.00003607975,0.008985692,0.0001248052,0.0001096035,0.00001220476,0.000601027,0.00004080388,0.9828871,0.00003343849,0.005979956,0.0007372697],"study_design_scores_gemma":[0.003824238,0.0006264233,0.01428966,0.00002929812,0.00001830988,0.00001045115,0.0006519826,0.001657409,0.9591671,0.00002005361,0.01938994,0.0003151851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961604,0.0006101934,0.0009531665,0.0006239864,0.00005028826,0.0004411646,0.00005450247,0.00007275908,0.001033557],"genre_scores_gemma":[0.9983975,0.0003611576,0.0004000412,0.0001291106,0.0002012415,0.00004173569,0.00008641186,0.0000554842,0.0003273368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02372007,"threshold_uncertainty_score":0.8439094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02737472838029147,"score_gpt":0.3524631148385412,"score_spread":0.3250883864582497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}