{"id":"W3036230532","doi":"10.1182/bloodadvances.2020001435","title":"Coinherited genetics of multiple myeloma and its precursor, monoclonal gammopathy of undetermined significance","year":2020,"lang":"en","type":"article","venue":"Blood Advances","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Center for Advancing Translational Sciences; Cancer Council Victoria; Mayo Clinic; Medical Research Council; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; University of Utah; Utah State University; Huntsman Cancer Institute; Utah Department of Health; National Health and Medical Research Council","keywords":"Monoclonal gammopathy of undetermined significance; Multiple myeloma; Monoclonal gammopathy; Medicine; Monoclonal; Paraproteinemias; Genetics; Internal medicine; Biology; Immunology; Monoclonal antibody; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000448204,0.0001447474,0.0003793543,0.0000474903,0.00002648,0.000004532908,0.00008604199,0.00004659451,0.00002740455],"category_scores_gemma":[0.0002886972,0.0001222911,0.00005962634,0.0001828922,0.0001166287,0.0000748406,0.0000487532,0.00008150424,0.000003813658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006688778,"about_ca_system_score_gemma":0.00007573434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008263574,"about_ca_topic_score_gemma":0.00001224174,"domain_scores_codex":[0.99889,0.00003868053,0.0002973261,0.0002662017,0.0002975365,0.0002102874],"domain_scores_gemma":[0.9991786,0.0001527433,0.0001431007,0.0001393024,0.0001443636,0.0002418499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001699748,0.0006296817,0.459355,0.001199285,0.0002696649,0.0001391116,0.0004655315,0.0000271553,0.4978047,0.00003709672,0.00001959586,0.03835341],"study_design_scores_gemma":[0.007107036,0.00237404,0.1753836,0.0001594759,0.0001577228,0.00002775949,0.0001224249,0.005605988,0.8076812,0.0000387301,0.001192913,0.0001491065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827625,0.01596789,0.00006100049,0.0002202576,0.00002154081,0.0005529377,0.0001294671,0.00002524606,0.0002591674],"genre_scores_gemma":[0.9925371,0.001645696,0.005575514,0.00004660188,0.00005080612,0.00002669847,0.00002234974,0.00001748845,0.00007778993],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3098764,"threshold_uncertainty_score":0.4986888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03770032261825722,"score_gpt":0.2966116267562429,"score_spread":0.2589113041379856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}