{"id":"W3036308450","doi":"10.1139/cjm-2020-0212","title":"A short overview of the CRISPR-Cas adaptation stage","year":2020,"lang":"en","type":"review","venue":"Canadian Journal of Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Biology; Adaptation (eye); Streptococcus thermophilus; Computational biology; Function (biology); Genome editing; Genome; Genetics; Bacteria; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005882049,0.001267996,0.001210306,0.002699882,0.0004310363,0.001279045,0.001128798,0.001314568,0.009081032],"category_scores_gemma":[0.0008634161,0.0005074508,0.0006816341,0.002544972,0.0004882172,0.001439362,0.0007192711,0.002565015,0.006001629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001367463,"about_ca_system_score_gemma":0.002088478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002498484,"about_ca_topic_score_gemma":0.003094647,"domain_scores_codex":[0.9997198,0.00003517045,0.00004399809,0.00006555934,0.0001004632,0.00003500047],"domain_scores_gemma":[0.9996253,0.0001753298,0.00004104226,0.00001350904,0.00009551416,0.00004923413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001232899,0.00007011975,0.0001574059,0.02288109,0.00006158563,0.000337038,0.00008121848,0.0004540368,0.005011364,0.007211813,0.07442703,0.8891841],"study_design_scores_gemma":[0.000006157695,0.0000545417,0.0002546064,0.001210883,0.00002828609,0.0005468146,0.000016981,0.00004425898,0.0006219212,0.0008752764,0.9963242,0.00001613266],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001842374,0.9912041,0.00101502,0.0007314767,0.0009975286,0.00003748565,0.0001532752,0.00008255481,0.005594303],"genre_scores_gemma":[0.0010862,0.992277,0.001441577,0.0007516589,0.000425627,0.00003761423,0.0002581819,0.00001221031,0.00370988],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.009081032,"threshold_uncertainty_score":0.03037912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04403859921477753,"score_gpt":0.3326118677707561,"score_spread":0.2885732685559786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}