{"id":"W3036364287","doi":"10.1074/jbc.ra119.010925","title":"The guanine nucleotide exchange factor VAV3 participates in ERBB4-mediated cancer cell migration","year":2020,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Turun Yliopistollinen Keskussairaala; Academy of Finland","keywords":"Guanine nucleotide exchange factor; ERBB4; ERBB3; Receptor tyrosine kinase; Epidermal growth factor receptor; Cell biology; Cancer research; Biology; ErbB; Signal transduction; Epidermal growth factor; Tyrosine phosphorylation; Tyrosine kinase; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007284315,0.0002841368,0.0001243385,0.0002116552,0.0003114972,0.0002766958,0.000131679,0.0003077833,0.00106407],"category_scores_gemma":[0.00007850314,0.00008600327,0.0003371096,0.0001499668,0.0001333103,0.0001298087,0.0002324948,0.0003148141,0.0004805617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004995627,"about_ca_system_score_gemma":0.0002403565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001898676,"about_ca_topic_score_gemma":0.0015733,"domain_scores_codex":[0.9999098,0.00001426959,0.000004399812,0.00001444879,0.00002212694,0.00003489633],"domain_scores_gemma":[0.9999663,0.000003465306,0.000008989118,0.000004068265,0.000006014083,0.00001134983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001264081,0.00002021599,0.0007622252,0.00003551696,0.000009969755,0.0001419688,0.00001821058,0.000109339,0.9958748,0.0003505255,0.0001527419,0.002398106],"study_design_scores_gemma":[0.00003363278,0.0001404889,0.02686316,0.00001471073,0.00003001295,0.001059823,0.00007193389,0.003614376,0.9572688,0.00034024,0.01055052,0.0000122178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909368,0.003721224,0.00205761,0.0001703169,0.00003368297,0.0000216457,0.0002770133,0.0001288874,0.0026529],"genre_scores_gemma":[0.9963242,0.0007884597,0.0008234816,0.00003481273,0.000004340701,0.00001219673,0.0002734929,0.00001012564,0.001728839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001898676,"threshold_uncertainty_score":0.003775179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1274528360611668,"score_gpt":0.3662935132493659,"score_spread":0.2388406771881991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}