{"id":"W3036413731","doi":"10.1016/j.jid.2020.05.033","title":"LB940 Ixekizumab versus guselkumab: 24-week clinical responses and 4-week gene expression data","year":2020,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Guenther Dermatology Research Centre","funders":"","keywords":"Ixekizumab; Medicine; Psoriasis; Internal medicine; Plaque psoriasis; Dosing; Surgery; Dermatology; Secukinumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008824227,0.0005669451,0.001424412,0.0004937348,0.0002909362,0.0007147776,0.0002944079,0.0009293712,0.004744594],"category_scores_gemma":[0.0008600443,0.0002187297,0.000823357,0.0004187823,0.0005258582,0.0007686225,0.0002094029,0.002108542,0.001356071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004875145,"about_ca_system_score_gemma":0.0003081979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005180308,"about_ca_topic_score_gemma":0.000535548,"domain_scores_codex":[0.9992321,0.0001771315,0.00006536271,0.0001488461,0.0001194679,0.0002570559],"domain_scores_gemma":[0.9993858,0.00018679,0.0001184959,0.00008460235,0.0000970599,0.000127104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2599141,0.0138712,0.01587432,0.0004858267,0.000467661,0.0005784312,0.0003479446,0.002597383,0.6034464,0.0001610646,0.003503949,0.09875169],"study_design_scores_gemma":[0.01081095,0.2821093,0.2460105,0.00008339748,0.001326149,0.001627526,0.001047365,0.006336607,0.4333543,0.000740397,0.01634836,0.0002050376],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922767,0.002329828,0.0005398205,0.0002454655,0.0001908811,0.000187402,0.001875651,0.00009039831,0.002263838],"genre_scores_gemma":[0.989693,0.0007146859,0.0008439106,0.0002558638,0.0001636591,0.0004109269,0.002218057,0.0000300659,0.005669902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004744594,"threshold_uncertainty_score":0.01587224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2073586184256714,"score_gpt":0.3404739827137998,"score_spread":0.1331153642881284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}