{"id":"W3036495611","doi":"10.1158/1557-3265.liqbiop20-a45","title":"Abstract A45: HPV sequencing facilitates ultrasensitive detection of HPV circulating tumor DNA","year":2020,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Occupational Cancer Research Centre","funders":"","keywords":"Medicine; Oncology; Internal medicine; Cervix; Minimal residual disease; Chemoradiotherapy; Cancer; Precision medicine; Adjuvant; Personalized medicine; Cervical cancer; Disease; Stage (stratigraphy); Pathology; Bioinformatics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001181833,0.0005302638,0.000409644,0.0003528684,0.0002731401,0.0008297106,0.000455048,0.0005991297,0.005525873],"category_scores_gemma":[0.001482725,0.000372041,0.0004422564,0.0002584659,0.0003989116,0.0004036544,0.0004401128,0.0006218911,0.00171779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003969953,"about_ca_system_score_gemma":0.0003854695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008877631,"about_ca_topic_score_gemma":0.001295533,"domain_scores_codex":[0.9990024,0.0002553882,0.00006045967,0.0003925202,0.0002252197,0.00006405851],"domain_scores_gemma":[0.9992515,0.0002565552,0.0001173545,0.0001120063,0.0002026625,0.00005990755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000420862,0.00009869492,0.005492404,0.0001309787,0.00004178001,0.00002343128,0.00006705148,0.0008895997,0.9773414,0.0001847666,0.0009383509,0.01437071],"study_design_scores_gemma":[0.00007246777,0.001194618,0.01581116,0.00003261261,0.0001168431,0.000316685,0.00005544989,0.02083651,0.950687,0.0004184307,0.01042,0.00003833042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.8545321,0.001886622,0.1256451,0.0005844385,0.0002624441,0.0004963714,0.009201974,0.002229991,0.005160909],"genre_scores_gemma":[0.8933826,0.0006215996,0.09140028,0.0007981729,0.00008358357,0.0005917923,0.007907717,0.0003083153,0.004905878],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.005525873,"threshold_uncertainty_score":0.01848596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1698895235382519,"score_gpt":0.4381968559618978,"score_spread":0.2683073324236459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}