{"id":"W3036606072","doi":"10.1371/journal.pone.0234375","title":"Quercetin treatment reduces the severity of renal dysplasia in a beta-catenin dependent manner","year":2020,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Biology; Renal dysplasia; Kidney; Beta-catenin; Catenin; Cancer research; Osteopontin; Kidney development; Internal medicine; Endocrinology; Pathology; Cell biology; Embryonic stem cell; Wnt signaling pathway; Medicine; Signal transduction; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001376889,0.0003566915,0.0003455062,0.0004670702,0.0001386183,0.0002185653,0.0002417783,0.0003917119,0.001408605],"category_scores_gemma":[0.0001389983,0.0001805633,0.0003081318,0.0001570975,0.0002063514,0.0002390798,0.0001443172,0.0006889884,0.0001258675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002408763,"about_ca_system_score_gemma":0.0002395509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001467672,"about_ca_topic_score_gemma":0.002722487,"domain_scores_codex":[0.9998689,0.00002383505,0.00001388656,0.00002658731,0.00004012374,0.00002652806],"domain_scores_gemma":[0.9998617,0.00001350167,0.00003844588,0.000009777775,0.00003536249,0.00004109549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002848586,0.000205293,0.0001714376,0.00005948419,0.00001748804,0.00002827616,0.00001215413,0.00004452947,0.996457,0.00004203632,0.00006547512,0.002611925],"study_design_scores_gemma":[0.0002567651,0.006753094,0.02322663,0.00003265065,0.0001356628,0.0003799766,0.00007205315,0.001561479,0.9628245,0.0001500388,0.00458308,0.00002414328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912635,0.003758156,0.002501522,0.0002448714,0.00004985763,0.00008229092,0.0003240423,0.0002340915,0.001541781],"genre_scores_gemma":[0.991358,0.002328709,0.00248308,0.0001431024,0.00001780127,0.00005581373,0.0005912731,0.00002106717,0.00300115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001467672,"threshold_uncertainty_score":0.004712284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0304514096071707,"score_gpt":0.2217066077647317,"score_spread":0.191255198157561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}