{"id":"W3036674396","doi":"10.1016/j.jaad.2020.06.055","title":"Efficacy and safety of topical terbinafine 10% solution (MOB-015) in the treatment of mild to moderate distal subungual onychomycosis: A randomized, multicenter, double-blind, vehicle-controlled phase 3 study","year":2020,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Nail Diseases and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mediprobe Research (Canada); University of Toronto","funders":"","keywords":"Medicine; Double blind; Terbinafine; Multicenter study; Dermatology; Nail disease; Randomized controlled trial; Surgery; Antifungal; Placebo; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001186054,0.001115569,0.002181833,0.0004259043,0.0004175776,0.0007725967,0.0009530522,0.001293883,0.003365041],"category_scores_gemma":[0.0007980738,0.000575047,0.001016637,0.0003102142,0.001114024,0.0007691903,0.0002284433,0.001747761,0.0006460696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004378947,"about_ca_system_score_gemma":0.0009500436,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009790373,"about_ca_topic_score_gemma":0.00169407,"domain_scores_codex":[0.9995585,0.0002123393,0.00002798307,0.00006866975,0.00004437925,0.00008809243],"domain_scores_gemma":[0.9995016,0.0001356325,0.0001091202,0.00004178256,0.00003189353,0.0001799187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9097937,0.02855141,0.0007691299,0.0006549829,0.0006155299,0.00007933982,0.0000915332,0.0003862065,0.02591735,0.0001331285,0.0005297351,0.032478],"study_design_scores_gemma":[0.695554,0.2961889,0.00406307,0.00002778298,0.0004482081,0.00007147031,0.00004177283,0.0005263682,0.002482566,0.00009804187,0.0004721226,0.00002554932],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959902,0.00168183,0.0004185208,0.0001119238,0.000104961,0.0008024595,0.0002059984,0.00005601771,0.0006281462],"genre_scores_gemma":[0.9952859,0.001396888,0.0006650633,0.0003080223,0.000139558,0.0006752376,0.00032139,0.00001463141,0.001193404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003365041,"threshold_uncertainty_score":0.01125717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03977989631949598,"score_gpt":0.3652875502802331,"score_spread":0.3255076539607371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}