{"id":"W3036787958","doi":"10.7554/elife.56910.sa2","title":"Author response: MxB sensitivity of HIV-1 is determined by a highly variable and dynamic capsid surface","year":2020,"lang":"en","type":"peer-review","venue":"","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Capsid; Cyclophilin A; Biology; Cell biology; Genetics; Molecular biology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001085422,0.0005110779,0.0004052288,0.0003865687,0.0005391638,0.001381975,0.000502061,0.001497194,0.2761648],"category_scores_gemma":[0.003660601,0.0002864482,0.0003679184,0.0004485144,0.0002991736,0.0008314565,0.0007693949,0.0008790168,0.08157527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005991591,"about_ca_system_score_gemma":0.0005493276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002228226,"about_ca_topic_score_gemma":0.000370304,"domain_scores_codex":[0.9986541,0.0003108424,0.0001146732,0.0002940205,0.0004656499,0.0001607027],"domain_scores_gemma":[0.9977008,0.0007019339,0.0002192384,0.0002197146,0.0008707516,0.0002876258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00123001,0.0001072623,0.005048097,0.0009056981,0.00004328713,0.0006345335,0.0001850533,0.0005069069,0.05164633,0.00299694,0.8494493,0.08724654],"study_design_scores_gemma":[0.0001901447,0.000301902,0.01065829,0.0002113723,0.00002384412,0.00095382,0.0005372762,0.001203789,0.05003091,0.002694155,0.9331269,0.00006759795],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.1483675,0.008256409,0.0266644,0.1825939,0.0929063,0.002071667,0.07398499,0.009102425,0.4560523],"genre_scores_gemma":[0.3043593,0.005658167,0.01101621,0.02776346,0.008045825,0.0008693594,0.02977053,0.002066354,0.6104508],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.2761648,"threshold_uncertainty_score":0.9238633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02004559141199301,"score_gpt":0.3026213913932301,"score_spread":0.2825757999812371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}