{"id":"W3036846341","doi":"10.1074/jbc.ra120.014464","title":"PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth","year":2020,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Division of Materials Research; National Center for Research Resources; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Science Foundation; Government of Canada; National Institutes of Health; Canadian Light Source","keywords":"Cancer research; Chemistry; Internal medicine; Oncology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001478114,0.0002512119,0.0002260209,0.0002967567,0.0001301777,0.000312195,0.0002218966,0.0002532686,0.00170793],"category_scores_gemma":[0.000254899,0.0001924465,0.0002777899,0.0001507752,0.0002927964,0.0001674476,0.0002492924,0.0005378457,0.0004442715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00038877,"about_ca_system_score_gemma":0.0003961629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00104515,"about_ca_topic_score_gemma":0.001808772,"domain_scores_codex":[0.9998099,0.00003245882,0.00001954349,0.00002756794,0.00006543482,0.00004512999],"domain_scores_gemma":[0.999599,0.00009521488,0.0001033847,0.000054135,0.00003192814,0.0001162234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001267069,0.00002059516,0.0002990339,0.00001475572,0.000002739443,0.00007464698,0.000004717776,0.00003721769,0.998811,0.00008520677,0.00003745555,0.0004859614],"study_design_scores_gemma":[0.00001554921,0.0002539074,0.004631845,0.000003013086,0.000007830652,0.0006080652,0.00002291469,0.000967918,0.9913192,0.00007114367,0.002094898,0.000003615728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931059,0.001163819,0.002943393,0.0001793582,0.00004353237,0.00002275314,0.0007459521,0.0001859059,0.001609309],"genre_scores_gemma":[0.994968,0.0003474767,0.001621208,0.00004233382,0.000006904897,0.00002074315,0.0009529826,0.00003581689,0.002004611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00170793,"threshold_uncertainty_score":0.005713642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0246775974521139,"score_gpt":0.2641261819896566,"score_spread":0.2394485845375428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}