{"id":"W3036919729","doi":"10.1038/s41375-020-0935-5","title":"Male predominance in AML is associated with specific preleukemic mutations","year":2020,"lang":"en","type":"letter","venue":"Leukemia","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Biology; Leukemia; Genetics; Preleukemia; Mutation; Hematology; Medicine; Cancer research; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0002137055,0.0007684621,0.001395366,0.0005649589,0.0001245519,0.00009458481,0.0006565416,0.001429031,0.001218891],"category_scores_gemma":[0.0003883486,0.0006957501,0.0002514338,0.001597409,0.0004297449,0.0001785971,0.000184396,0.007584709,0.001130716],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01234593,"about_ca_system_score_gemma":0.005039679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002786663,"about_ca_topic_score_gemma":0.00005614287,"domain_scores_codex":[0.9949778,0.0002232652,0.0008107839,0.001392423,0.001328297,0.001267398],"domain_scores_gemma":[0.9974167,0.0005173459,0.0003971205,0.001119226,0.0002948189,0.0002547514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003275431,0.00003930024,0.002867382,0.0003437761,0.0002514864,0.02009619,0.0007019283,0.00002670169,0.0003781801,0.000006433866,0.9743678,0.0005933022],"study_design_scores_gemma":[0.009090981,0.0007000273,0.006770111,0.002264975,0.0003060666,0.001423783,0.0001046496,0.002028548,0.0009278184,0.0001513776,0.9751486,0.001083127],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.1530561,0.001214277,0.0001635268,0.8127954,0.0003430688,0.004137565,0.0007084575,0.0004958648,0.02708575],"genre_scores_gemma":[0.05644411,0.0007420366,0.002098116,0.8147132,0.004344439,0.0007711881,0.005643197,0.0006263405,0.1146173],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.09661201,"threshold_uncertainty_score":0.9998673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02285359932203269,"score_gpt":0.2645555930208941,"score_spread":0.2417019936988614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}