{"id":"W3036965580","doi":"10.1111/acel.13174","title":"Mybl2 rejuvenates heart explant‐derived cells from aged donors after myocardial infarction","year":2020,"lang":"en","type":"article","venue":"Aging Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Senescence; Paracrine signalling; Biology; Myocardial infarction; Stem cell; Cell therapy; Medicine; Immunology; Cancer research; Cell biology; Internal medicine; Cardiology; Andrology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001129168,0.0001843258,0.0001744391,0.00003595377,0.00007695696,0.00005148833,0.0002037682,0.0001381807,0.000111797],"category_scores_gemma":[0.00002073032,0.0001882571,0.0001301965,0.00009392553,0.00006606638,0.000008142213,0.0002204389,0.0002012278,0.0002813463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000016455,"about_ca_system_score_gemma":0.0000476757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002065989,"about_ca_topic_score_gemma":0.00001835159,"domain_scores_codex":[0.9985821,0.0001367716,0.0001927174,0.0005195389,0.0002156762,0.000353188],"domain_scores_gemma":[0.9993914,0.00002532687,0.00004983477,0.0003038952,0.00004071815,0.0001887993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001423997,0.00002340266,0.004513184,0.00002064658,0.0000396582,0.00002066459,0.0002788853,0.00009654603,0.9841493,1.246624e-7,0.01058327,0.0001319177],"study_design_scores_gemma":[0.0005672578,0.0001046949,0.005520776,0.00001154124,0.00001676688,0.000002015297,0.0001201525,0.0001236541,0.9296908,0.000007754908,0.06361184,0.000222748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996311,0.0007054525,0.0003146713,0.001189924,0.0002488665,0.0001925932,0.00005672418,0.00003745525,0.0009433163],"genre_scores_gemma":[0.9958826,0.0003249797,0.0005143267,0.002020655,0.0005176815,0.00002466061,0.0002698371,0.0000369597,0.0004082822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0544585,"threshold_uncertainty_score":0.7676899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01034694249127062,"score_gpt":0.2230863000537298,"score_spread":0.2127393575624591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}