{"id":"W3036965580","doi":"10.1111/acel.13174","title":"Mybl2 rejuvenates heart explant‐derived cells from aged donors after myocardial infarction","year":2020,"lang":"en","type":"article","venue":"Aging Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Senescence; Paracrine signalling; Biology; Myocardial infarction; Stem cell; Cell therapy; Medicine; Immunology; Cancer research; Cell biology; Internal medicine; Cardiology; Andrology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003924349,0.0003252249,0.0004642584,0.0002337294,0.0001695405,0.0004340678,0.0002099896,0.0003183244,0.002724924],"category_scores_gemma":[0.0001152682,0.0001779463,0.0003058372,0.0001342522,0.0001784118,0.0002237779,0.00023231,0.0009840149,0.0008671841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009208069,"about_ca_system_score_gemma":0.0001532235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001997383,"about_ca_topic_score_gemma":0.0004263627,"domain_scores_codex":[0.999818,0.00002297358,0.00002459005,0.00005281418,0.00003406367,0.00004753205],"domain_scores_gemma":[0.9998575,0.00001678543,0.00003240952,0.00002173205,0.00001206734,0.00005948926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006005294,0.00018174,0.0003710061,0.00005475498,0.000008909561,0.00008108608,0.00004215377,0.00004095869,0.9965584,0.00006363889,0.0001065827,0.001890288],"study_design_scores_gemma":[0.0002481919,0.003686229,0.02036643,0.00004369161,0.00008466053,0.0009370459,0.0001886872,0.00119946,0.9647869,0.0001112776,0.008331457,0.00001598425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928874,0.002355328,0.002404585,0.0001533197,0.0001717484,0.00006443181,0.0007025024,0.00009030156,0.001170301],"genre_scores_gemma":[0.9877325,0.001646252,0.002695269,0.0002698924,0.00007841539,0.0001557364,0.001599021,0.00005750194,0.005765331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002724924,"threshold_uncertainty_score":0.009115756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01034694249127062,"score_gpt":0.2230863000537298,"score_spread":0.2127393575624591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}