{"id":"W3037240981","doi":"10.7554/elife.55294","title":"Different methods of fear reduction are supported by distinct cortical substrates","year":2020,"lang":"en","type":"article","venue":"eLife","topic":"Memory and Neural Mechanisms","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Brain and Behavior Research Foundation; Canada Research Chairs; Fonds de Recherche du Québec - Santé","keywords":"Anxiety; Fear processing in the brain; Infralimbic cortex; Orbitofrontal cortex; Psychology; Neuroscience; Extinction (optical mineralogy); Fear conditioning; Novelty; Cortex (anatomy); Aversive Stimulus; Cognitive psychology; Amygdala; Prefrontal cortex; Cognition; Social psychology; Psychiatry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107155,0.000111657,0.0002015062,0.00001564699,0.00007188509,0.000015075,0.0001425617,0.00004723321,0.0003462357],"category_scores_gemma":[0.0009262816,0.00008865296,0.00005604275,0.0001535776,0.00007415757,0.00006356979,0.00004026729,0.0001739379,0.00003238808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006804138,"about_ca_system_score_gemma":0.00001005456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":8.907785e-7,"about_ca_topic_score_gemma":2.563109e-7,"domain_scores_codex":[0.9987283,0.0003207775,0.0002415195,0.0003063532,0.0002355951,0.0001674534],"domain_scores_gemma":[0.9994227,0.0001318331,0.0001182515,0.0001344524,0.00002118184,0.0001715263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005083877,0.00005659797,0.0001947173,0.00002252192,0.000001948853,0.000008492986,0.0000816216,8.715337e-7,0.9977386,0.0002343845,0.001127253,0.0004821313],"study_design_scores_gemma":[0.0001679094,0.0001853626,0.003164036,0.000008556892,0.0000126433,0.00001066189,0.00007034616,0.0005669584,0.9954633,0.0001063866,0.0001519637,0.00009185931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967847,0.00001973483,0.001428731,0.00111327,0.0002803143,0.0001291375,0.0000311544,0.00007539283,0.0001375274],"genre_scores_gemma":[0.9990006,0.00001580106,0.000315161,0.0004518223,0.00007619816,0.000006132515,0.000005229138,0.00001155245,0.0001175055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002969319,"threshold_uncertainty_score":0.3791038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1482432451532839,"score_gpt":0.3722393787919033,"score_spread":0.2239961336386195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}