{"id":"W3037252826","doi":"10.3389/fphys.2020.00609","title":"Study of sRAGE, HMGB1, AGE, and S100A8/A9 Concentrations in Plasma and in Serum-Extracted Extracellular Vesicles of Pregnant Women With Preterm Premature Rupture of Membranes","year":2020,"lang":"en","type":"article","venue":"Frontiers in Physiology","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Medicine; Inflammation; HMGB1; Chorioamnionitis; Pregnancy; S100A8; Internal medicine; Gestation; Placenta; Premature rupture of membranes; Fetus; Glycation; Gestational age; Extracellular; Immunology; Endocrinology; Andrology; Receptor; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007179564,0.0001529309,0.0007128651,0.0001296298,0.00001171715,0.000002952198,0.00008560497,0.000147801,0.000007696441],"category_scores_gemma":[0.00005286177,0.0001249695,0.00001709445,0.0002539265,0.0002374405,0.00008428773,0.00003880301,0.0002626465,3.650792e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001962858,"about_ca_system_score_gemma":0.00005902928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000223585,"about_ca_topic_score_gemma":0.00008356315,"domain_scores_codex":[0.9988275,0.000132794,0.0004284056,0.0002833517,0.0001137716,0.0002141889],"domain_scores_gemma":[0.9994751,0.00005253686,0.0001887804,0.0001656027,0.00003586262,0.00008217173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004171025,0.0006752189,0.6560662,0.0016231,0.0001362751,0.0002218514,0.04327198,0.0001614705,0.2919153,0.00001419346,0.00004789283,0.001695482],"study_design_scores_gemma":[0.006052419,0.002203121,0.9638464,0.0005422449,0.00004260847,0.00001250151,0.01030859,0.0008314608,0.01588428,0.0001249998,0.00002499789,0.0001264051],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966751,0.002319389,0.000007027617,0.00006911139,0.00004687928,0.0007995715,0.00003837946,0.000007775632,0.00003675405],"genre_scores_gemma":[0.9989718,0.0004494336,0.0004580153,0.00002711712,0.00001568023,0.00003814278,0.00001692698,0.00001211319,0.00001078101],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3077801,"threshold_uncertainty_score":0.5096109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009810989132559933,"score_gpt":0.2217665908909325,"score_spread":0.2119556017583726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}