{"id":"W3037267669","doi":"10.1080/10717544.2020.1785048","title":"Engineering of fluorescent or photoactive Trojan probes for detection and eradication of β-Amyloids","year":2020,"lang":"en","type":"article","venue":"Drug Delivery","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor; Wilfrid Laurier University","funders":"","keywords":"Trojan horse; Drug delivery; Nanotechnology; Fluorescence; Nanomedicine; Molecular imaging; Blood–brain barrier; Materials science; Neuroscience; Biomedical engineering; Computer science; Nanoparticle; Medicine; Biology; Biotechnology; Central nervous system; In vivo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004847359,0.00006181462,0.0001022189,0.00002589014,0.00001438711,0.000002457361,0.00003484623,0.00004349965,3.528532e-7],"category_scores_gemma":[0.00005263206,0.00005160341,0.00004619681,0.00005948617,0.00003031259,0.000002923377,0.00001999752,0.00002414445,5.151867e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005578042,"about_ca_system_score_gemma":0.00001345012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007899634,"about_ca_topic_score_gemma":0.000007062938,"domain_scores_codex":[0.9996234,0.000009261351,0.0001211761,0.0001417967,0.00004251993,0.00006187523],"domain_scores_gemma":[0.9997405,0.00001008976,0.00007419875,0.0000698779,0.00007801193,0.00002726773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002330149,0.00001629179,0.00005857936,0.0000549369,0.00003811179,1.10347e-7,0.0001183644,0.00001831376,0.9902396,0.000002108077,0.00002725105,0.009193322],"study_design_scores_gemma":[0.0001736212,0.0002097634,0.0001643791,0.00001429189,0.00003223465,8.966254e-7,0.0001071984,0.003686897,0.9949097,0.00000474939,0.0006363401,0.00005993784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863131,0.0001580212,0.01326241,0.0000641285,0.00001006509,0.0001562022,0.00001888498,0.00001172956,0.000005456029],"genre_scores_gemma":[0.9925933,0.000230582,0.00705268,0.00003173652,0.00004457746,0.000008519276,0.00002216818,0.000007027791,0.00000935011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009133384,"threshold_uncertainty_score":0.2104326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009106572786611157,"score_gpt":0.2300180761477391,"score_spread":0.220911503361128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}