{"id":"W3037293035","doi":"10.1124/mol.120.119644","title":"Heteromeric Assembly of Truncated Neuronal Kv7 Channels: Implications for Neurologic Disease and Pharmacotherapy","year":2020,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta","keywords":"Pharmacotherapy; Neuroscience; Disease; Medicine; Biology; Pathology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006194775,0.0001504111,0.0001542287,0.00004669158,0.0000637484,0.000008960214,0.000121194,0.00007570555,0.00003070814],"category_scores_gemma":[0.00004700181,0.0001546398,0.0001015007,0.0001228988,0.00008661465,0.000005092069,0.000053578,0.0000632411,0.000001786958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004253035,"about_ca_system_score_gemma":0.00004238857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":7.531096e-7,"about_ca_topic_score_gemma":6.558713e-8,"domain_scores_codex":[0.9990553,0.0001053275,0.0002031542,0.0003836324,0.00005767737,0.000194866],"domain_scores_gemma":[0.9994726,0.00002242777,0.0001067833,0.0001016725,0.0001018577,0.000194639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007186756,0.0000716157,0.0003087831,0.00003584599,0.00007090607,0.000001751254,0.00001996636,0.001700856,0.993396,0.00009250542,0.002450399,0.001132652],"study_design_scores_gemma":[0.00305528,0.001220658,0.004856511,0.000001249678,0.0001449893,0.00001001401,0.000007039993,0.0164189,0.9318562,0.0001295805,0.04204667,0.0002529007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9562359,0.0006008938,0.03266797,0.009297764,0.0004823696,0.0005821401,0.00007452122,0.00002905492,0.00002942267],"genre_scores_gemma":[0.9882316,0.0001594734,0.0001406669,0.0106348,0.0003764025,0.0001575556,0.0002373928,0.00002864528,0.00003344929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06153984,"threshold_uncertainty_score":0.6306029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02846808972468022,"score_gpt":0.3030575238656273,"score_spread":0.2745894341409471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}