{"id":"W3037380067","doi":"10.1128/msphere.00235-20","title":"Characterization of a Type II-A CRISPR-Cas System in <i>Streptococcus mutans</i>","year":2020,"lang":"en","type":"article","venue":"mSphere","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"University of Toronto; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada","keywords":"CRISPR; Streptococcus mutans; Biology; Genome editing; Computational biology; Adaptation (eye); Bacteria; Microbiology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002278327,0.0002897583,0.0002650127,0.0003423634,0.0002031682,0.0003900372,0.0003453574,0.0003328634,0.001502438],"category_scores_gemma":[0.0003894973,0.000146956,0.0004219587,0.0002727822,0.0001615757,0.0001842457,0.0001843221,0.0006870931,0.001263842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004267065,"about_ca_system_score_gemma":0.0004313563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00250777,"about_ca_topic_score_gemma":0.001931047,"domain_scores_codex":[0.999761,0.00003291728,0.00003812046,0.00004366853,0.00009116913,0.00003304637],"domain_scores_gemma":[0.9997681,0.00004707137,0.0000637662,0.00003401474,0.00003732918,0.00004978223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003036836,0.0000327924,0.0001962982,0.00002407551,0.000004096321,0.00004014787,0.00001153182,0.00009598378,0.9982268,0.0001177733,0.00004643752,0.001173767],"study_design_scores_gemma":[0.000007025608,0.0002147128,0.004777906,0.000008070648,0.00001524993,0.0003128932,0.00002303843,0.001276971,0.9874631,0.00007140824,0.005818425,0.00001105048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9466701,0.0008358242,0.04126869,0.0003562517,0.000090623,0.0003130054,0.004783802,0.0005148587,0.005166952],"genre_scores_gemma":[0.9466591,0.0004395109,0.03380525,0.0001338259,0.00001376794,0.0001330006,0.009083906,0.0001565072,0.009575024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00250777,"threshold_uncertainty_score":0.005026102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007599037939071524,"score_gpt":0.2518717941244097,"score_spread":0.2442727561853382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}