{"id":"W3037431558","doi":"10.1186/s12861-020-00217-1","title":"Wingless and Archipelago, a fly E3 ubiquitin ligase and a homolog of human tumor suppressor FBW7, show an antagonistic relationship in wing development","year":2020,"lang":"en","type":"article","venue":"BMC Developmental Biology","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Research Foundation of Korea; National Research Foundation","keywords":"Gene knockdown; Biology; Ubiquitin; Ubiquitin ligase; Cell biology; Wnt signaling pathway; Endoplasmic reticulum; Signal transduction; Cell culture; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009080707,0.0005091197,0.0002281094,0.0003255165,0.0001739748,0.0003071334,0.0002684109,0.0003695493,0.00171561],"category_scores_gemma":[0.00008137944,0.0001934783,0.0002945146,0.0001825773,0.0003078126,0.000149763,0.0004866936,0.0004119822,0.0008620922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003834052,"about_ca_system_score_gemma":0.0001973618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003874484,"about_ca_topic_score_gemma":0.0008988518,"domain_scores_codex":[0.9998339,0.00001256746,0.00001054264,0.00004329348,0.00006369388,0.0000360693],"domain_scores_gemma":[0.9998811,0.000007677133,0.00003905606,0.000007715154,0.00001411271,0.00005026874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008887458,0.00001074559,0.0008543513,0.00004012181,0.00001266101,0.0001532999,0.000007314239,0.00003630875,0.9962476,0.0002580055,0.00009894358,0.002191682],"study_design_scores_gemma":[0.00002979932,0.0002328306,0.03669923,0.00001377765,0.00005555997,0.002521405,0.0000499011,0.001157329,0.9413327,0.0002373018,0.01766121,0.000008975317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9751109,0.0119227,0.004228181,0.0002144905,0.00007194213,0.00003553882,0.0005509124,0.0001731263,0.007692274],"genre_scores_gemma":[0.9803311,0.001804752,0.00196634,0.0001326052,0.00001317803,0.00004081642,0.001303661,0.00002772042,0.01437979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00171561,"threshold_uncertainty_score":0.005739272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04228430803156202,"score_gpt":0.2793036426097438,"score_spread":0.2370193345781818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}