{"id":"W3037538436","doi":"10.1093/jac/dkaa220","title":"Emergence of vancomycin- and teicoplanin-resistant Enterococcus faecium via vanD5-harbouring large genomic island","year":2020,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Education, Culture, Sports, Science and Technology; Japan Agency for Medical Research and Development","keywords":"Enterococcus faecium; Teicoplanin; Biology; Microbiology; Vancomycin; Enterococcus; Genome; Gene; Genetics; Staphylococcus aureus; Bacteria; Antibiotics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001002463,0.0002470484,0.0001561678,0.0002487449,0.0001579487,0.0004009278,0.0002320665,0.0002711856,0.0007744],"category_scores_gemma":[0.0003756781,0.0001360081,0.0003095371,0.0002882341,0.0001838028,0.0001456795,0.0003315115,0.0003182634,0.0002018769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003090102,"about_ca_system_score_gemma":0.0002626374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003152988,"about_ca_topic_score_gemma":0.005708887,"domain_scores_codex":[0.9998579,0.00001365645,0.00001734626,0.00003901916,0.00003230972,0.00003971035],"domain_scores_gemma":[0.9997467,0.00003908662,0.00009644203,0.00002163948,0.00005031353,0.00004584364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003803511,0.0001272609,0.108092,0.0001764962,0.00008091635,0.005663844,0.0002818409,0.000340277,0.8728935,0.0003855068,0.0003200902,0.01125803],"study_design_scores_gemma":[0.0001157715,0.001125115,0.7134401,0.0001138704,0.0002055421,0.04435643,0.001509135,0.003299504,0.2206567,0.0002751132,0.0148346,0.00006813602],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984213,0.0001674204,0.0006741599,0.00002710572,0.000004674169,0.00001581474,0.0001579979,0.00001157988,0.0005199376],"genre_scores_gemma":[0.9968452,0.0001080901,0.001578443,0.00004197897,0.000003846419,0.000005254033,0.000828917,0.000008691946,0.0005796344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003152988,"threshold_uncertainty_score":0.006269276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01103398065020987,"score_gpt":0.2488966845401344,"score_spread":0.2378627038899246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}