{"id":"W3037545866","doi":"10.1038/s41380-020-0822-5","title":"The IMAGEN study: a decade of imaging genetics in adolescents","year":2020,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Baycrest Hospital; University of Toronto","funders":"National Institute of Biomedical Imaging and Bioengineering; Medical Research Council; National Institutes of Health; National Institute of Mental Health; Vetenskapsrådet; Svenska Forskningsrådet Formas; EU Joint Programme – Neurodegenerative Disease Research; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Mission Interministérielle de Lutte Contre les Drogues et les Conduites Addictives; Science Foundation Ireland; Deutsche Forschungsgemeinschaft; King's College London; Fondation de France; Bundesministerium für Bildung und Forschung; National Institute for Health and Care Research; European Commission; South London and Maudsley NHS Foundation Trust","keywords":"Generalizability theory; Imaging genetics; Sample size determination; Psychology; Longitudinal sample; Neuroimaging; Brain Structure and Function; Longitudinal study; Neuroscience; Anticipation (artificial intelligence); Neurogenetics; Cognitive psychology; Developmental psychology; Biology; Genetics; Medicine; Gene; Artificial intelligence; Computer science; Statistics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004947364,0.0003928742,0.0009344079,0.00008577015,0.00008180908,0.00002189497,0.0007413471,0.0002325148,0.00000184485],"category_scores_gemma":[0.0001800597,0.0003099252,0.000490507,0.0003068365,0.00008514597,0.000001036795,0.0003510306,0.0003413695,0.00001287279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003121976,"about_ca_system_score_gemma":0.0004775059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000172831,"about_ca_topic_score_gemma":0.00009502267,"domain_scores_codex":[0.9971373,0.0006914056,0.0009562122,0.0006238163,0.0001839831,0.0004072968],"domain_scores_gemma":[0.9985009,0.0000192041,0.0005425072,0.0007826213,0.0000640811,0.00009067197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003186548,0.0005574739,0.09024246,0.002528386,0.0006992361,0.00004191933,0.00006434645,0.00003354885,0.000145218,0.00005959391,0.002643997,0.902952],"study_design_scores_gemma":[0.0007001407,0.00024593,0.005075238,0.001384655,0.0005630736,0.00003177359,0.0002025541,0.00003050585,0.00001304114,0.0001695734,0.9910354,0.0005480927],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001726545,0.9959649,0.0005041863,0.0001888083,0.0004739745,0.0009570013,0.00002343243,0.0000069778,0.0001541552],"genre_scores_gemma":[0.01193602,0.9865472,0.0008573973,0.0001839885,0.0001910835,0.000111787,0.00006399139,0.00008183652,0.0000266384],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9883914,"threshold_uncertainty_score":0.9999353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01401765403935022,"score_gpt":0.324097316129775,"score_spread":0.3100796620904248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}