{"id":"W3037708341","doi":"10.1128/msphere.00521-20","title":"Doesn’t It All Come Down to Function? How To Correlate VAR2CSA Antibodies with Protection","year":2020,"lang":"en","type":"letter","venue":"mSphere","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Antibody; Function (biology); Computer science; Virology; Medicine; Immunology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001085681,0.0006377025,0.0007118342,0.0001360652,0.0004514205,0.0001125291,0.0005364632,0.000988039,0.001744339],"category_scores_gemma":[0.00005491054,0.0005085634,0.0001866823,0.0004175676,0.0001744603,0.0001307005,0.0001949328,0.002441508,0.006638146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008578484,"about_ca_system_score_gemma":0.000099184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003066171,"about_ca_topic_score_gemma":0.00004152457,"domain_scores_codex":[0.9976075,0.0002272566,0.0003574969,0.0008752937,0.0001199061,0.0008125673],"domain_scores_gemma":[0.9989406,0.00005601143,0.0002111708,0.0006378565,0.0001347775,0.00001957051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005229132,0.00006002215,0.0000382432,0.000145195,0.000617924,0.00008279929,0.001098172,0.00009701032,0.01334524,0.0000220177,0.9790041,0.004966345],"study_design_scores_gemma":[0.0008077049,0.001168562,0.0006033441,0.000242765,0.0001920068,0.00006917561,0.0006103421,0.000002265025,0.0007640555,0.0000478362,0.9947408,0.0007510907],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.003105553,0.005360825,0.003332395,0.977739,0.00359904,0.002091003,0.0001463729,0.0004550898,0.004170693],"genre_scores_gemma":[0.08565737,0.0000520913,0.00007966522,0.8188151,0.0001604805,0.0004042151,0.001254558,0.0001421224,0.09343444],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.158924,"threshold_uncertainty_score":0.9998599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01385209266737714,"score_gpt":0.2094376029428996,"score_spread":0.1955855102755224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}