{"id":"W3037804099","doi":"10.1056/nejmoa1916624","title":"Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes","year":2020,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Gout, Hyperuricemia, Uric Acid","field":"Medicine","cited_by":357,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; LMC Diabetes & Endocrinology (Canada); Lunenfeld-Tanenbaum Research Institute; University of Calgary; University of Toronto; University Health Network","funders":"National Center for Advancing Translational Sciences; National Institute on Aging; National Institutes of Health; Steno Diabetes Center Copenhagen; National Institute of Diabetes and Digestive and Kidney Diseases; Juvenile Diabetes Research Foundation United States of America","keywords":"Allopurinol; Renal function; Type 2 diabetes; Medicine; Gout; Hyperuricemia; Internal medicine; Uric acid; Diabetes mellitus; Endocrinology; Cardiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00406387,0.000291317,0.0008661514,0.0003965088,0.0001468236,0.0006693989,0.0003940946,0.0006216037,0.001952976],"category_scores_gemma":[0.007991366,0.0001032019,0.001017664,0.0007838756,0.0002745081,0.000340344,0.0003122316,0.0009844932,0.0001052174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005356266,"about_ca_system_score_gemma":0.0007003359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001746222,"about_ca_topic_score_gemma":0.002212211,"domain_scores_codex":[0.9976317,0.001651996,0.0001644314,0.0001316695,0.0003282476,0.00009195644],"domain_scores_gemma":[0.9951094,0.002631027,0.001698463,0.0001180575,0.0001796501,0.0002634506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.07296696,0.00268891,0.27077,0.01002242,0.01215801,0.0003257106,0.0001460089,0.001648287,0.001250525,0.0009552793,0.005875824,0.621192],"study_design_scores_gemma":[0.01337174,0.03402865,0.9123905,0.003872155,0.01387141,0.001045477,0.0001869509,0.002609204,0.001185162,0.003305439,0.01407044,0.00006281667],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.4370998,0.5464931,0.0009599765,0.006769665,0.0007889562,0.000129122,0.0006707048,0.00005483384,0.007033896],"genre_scores_gemma":[0.9453612,0.05088941,0.0006917553,0.001589275,0.0007905792,0.00006239075,0.0002264155,0.000003809394,0.0003852373],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00406387,"threshold_uncertainty_score":0.02149206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01580226948444473,"score_gpt":0.2284351778353282,"score_spread":0.2126329083508834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}