{"id":"W3037829129","doi":"10.1038/s41409-020-0982-6","title":"Allogeneic haematopoietic stem cell transplantation improves outcome of adults with relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia entering remission following CD19 chimeric antigen receptor T cells","year":2020,"lang":"en","type":"article","venue":"Bone Marrow Transplantation","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ministry of Agriculture","funders":"","keywords":"Medicine; Haematopoiesis; Stem cell; Transplantation; Acute lymphocytic leukemia; Chimeric antigen receptor; CD19; Philadelphia chromosome; Immunology; Refractory (planetary science); Leukemia; Hematopoietic stem cell transplantation; Acute leukemia; Lymphoblastic Leukemia; Internal medicine; Antigen; Oncology; Cancer research; T cell; Chromosomal translocation; Biology; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001454382,0.0001700223,0.0003410729,0.0001015929,0.0001022589,0.0001789561,0.00009927544,0.0001313426,0.001078006],"category_scores_gemma":[0.0003626602,0.00003960908,0.000142537,0.0001203401,0.0001237494,0.0001341103,0.0001023813,0.0003256854,0.0002250112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009064893,"about_ca_system_score_gemma":0.00009911189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002995406,"about_ca_topic_score_gemma":0.0006662967,"domain_scores_codex":[0.9999616,0.00001054151,0.000003866342,0.00000547785,0.000005026853,0.00001357487],"domain_scores_gemma":[0.9998976,0.00001839965,0.00002404386,0.000009255917,0.000005303231,0.0000454236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.1289274,0.006019865,0.226377,0.0004502176,0.0006016243,0.006478551,0.0008948917,0.002019685,0.1093341,0.0004957313,0.00541353,0.5129876],"study_design_scores_gemma":[0.005738076,0.09137703,0.866927,0.00009182876,0.0009174856,0.009194541,0.0004546426,0.001532602,0.01488275,0.0004713172,0.008393149,0.00001957229],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982279,0.0006882345,0.00008421326,0.00008185833,0.00002396724,0.00001215376,0.00006854388,0.00001623556,0.0007968753],"genre_scores_gemma":[0.9991539,0.0003034667,0.00005224714,0.00005722596,0.00002562881,0.000005148323,0.0001752553,0.000002652461,0.0002244874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001078006,"threshold_uncertainty_score":0.003606319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360999500684993,"score_gpt":0.2478743851934916,"score_spread":0.2342643901866417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}