{"id":"W3037968627","doi":"10.1164/rccm.202003-0729le","title":"Blood Eosinophil Depletion with Mepolizumab, Benralizumab, and Prednisolone in Eosinophilic Asthma","year":2020,"lang":"en","type":"letter","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute for Health and Care Research; Wellcome Trust","keywords":"Benralizumab; Mepolizumab; Medicine; Prednisolone; Eosinophil; Immunology; Asthma; Eosinophilic; Dermatology; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001185554,0.0006282206,0.0008317576,0.0005996576,0.002247339,0.001046101,0.0008923677,0.01404786,0.00186977],"category_scores_gemma":[0.006648648,0.0003667205,0.0008643577,0.0003491306,0.001024478,0.001002689,0.0004416108,0.0082913,0.0012488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002710072,"about_ca_system_score_gemma":0.001562895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004548324,"about_ca_topic_score_gemma":0.007685647,"domain_scores_codex":[0.9991444,0.0003426629,0.0001089019,0.00006018957,0.0001956914,0.0001481593],"domain_scores_gemma":[0.9982876,0.0009359873,0.00009387787,0.00004700203,0.0002133088,0.0004221937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001207916,0.0005293503,0.01397311,0.0002395049,0.0001401755,0.2711419,0.0003117669,0.0007165942,0.001976564,0.004802078,0.6704075,0.03455359],"study_design_scores_gemma":[0.003503982,0.002119384,0.05534733,0.00154579,0.0005176515,0.3019779,0.001233453,0.01445937,0.003272992,0.02471752,0.5910926,0.0002120526],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.03425942,0.008619766,0.0008031889,0.8953912,0.02604692,0.0001271406,0.0001676286,0.000127979,0.03445666],"genre_scores_gemma":[0.2732993,0.00655269,0.001795603,0.6064736,0.08777346,0.0001705856,0.0002245839,0.00007269468,0.02363748],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.01404786,"threshold_uncertainty_score":0.01966304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01352261019483043,"score_gpt":0.2771498190734066,"score_spread":0.2636272088785762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}