{"id":"W3038245647","doi":"10.1111/ajt.16174","title":"Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes","year":2020,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; University of Illinois at Chicago; University of Illinois at Urbana-Champaign; Uppsala Universitet; University of Minnesota; University of California, San Francisco; Novo Nordisk Fonden; Northwestern University; University of Alberta; Deutsches Krebsforschungszentrum; Emory University; National Center for Research Resources; University of Pennsylvania; Georgia Clinical and Translational Science Alliance; National Institute of Diabetes and Digestive and Kidney Diseases; University of Iowa; University of Miami","keywords":"Medicine; Type 1 diabetes; Hypoglycemia; Transplantation; Diabetes mellitus; Islet; Type 2 diabetes; Internal medicine; Clinical endpoint; Insulin; Randomized controlled trial; Kidney transplantation; Intensive care medicine; Surgery; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002632927,0.002293258,0.003558288,0.0004519866,0.0007782547,0.002178095,0.001485217,0.002014471,0.006702692],"category_scores_gemma":[0.001072115,0.000506408,0.003101632,0.0004893946,0.001670431,0.00142041,0.0006528691,0.006709692,0.00116487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001530635,"about_ca_system_score_gemma":0.002717803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00187889,"about_ca_topic_score_gemma":0.00335822,"domain_scores_codex":[0.9992915,0.0003135981,0.0000220948,0.0001056157,0.00004105646,0.0002260486],"domain_scores_gemma":[0.9989995,0.0002273641,0.0001276909,0.0001196171,0.00004091589,0.0004849158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9375046,0.03168527,0.001136462,0.0003239998,0.0007634592,0.0001016063,0.000072897,0.001049537,0.004996909,0.0002197532,0.001901991,0.02024363],"study_design_scores_gemma":[0.8151622,0.1792456,0.002604684,0.00003910672,0.0002610024,0.00006886213,0.00004004327,0.0004045155,0.0009818836,0.0002470398,0.0009250705,0.00001994979],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988917,0.003258405,0.0006145462,0.001064879,0.0006247733,0.001627074,0.00124359,0.0001482976,0.002501376],"genre_scores_gemma":[0.9817373,0.002797534,0.00178368,0.002906388,0.0005706776,0.002738598,0.003504319,0.00007320908,0.003888384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006702692,"threshold_uncertainty_score":0.02242273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01825069058503744,"score_gpt":0.2959066989232209,"score_spread":0.2776560083381835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}