{"id":"W3038245647","doi":"10.1111/ajt.16174","title":"Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes","year":2020,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; University of Illinois at Chicago; University of Illinois at Urbana-Champaign; Uppsala Universitet; University of Minnesota; University of California, San Francisco; Novo Nordisk Fonden; Northwestern University; University of Alberta; Deutsches Krebsforschungszentrum; Emory University; National Center for Research Resources; University of Pennsylvania; Georgia Clinical and Translational Science Alliance; National Institute of Diabetes and Digestive and Kidney Diseases; University of Iowa; University of Miami","keywords":"Medicine; Type 1 diabetes; Hypoglycemia; Transplantation; Diabetes mellitus; Islet; Type 2 diabetes; Internal medicine; Clinical endpoint; Insulin; Randomized controlled trial; Kidney transplantation; Intensive care medicine; Surgery; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001924082,0.0001083353,0.0004660141,0.0002181082,0.00001559404,0.000006536623,0.00005344958,0.00003276492,0.000108715],"category_scores_gemma":[0.00007587361,0.00009410243,0.0001147321,0.0004328982,0.00009013358,0.0001423235,0.000001071869,0.0001562693,0.000004128224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002127434,"about_ca_system_score_gemma":0.0001169063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002056598,"about_ca_topic_score_gemma":0.000001608776,"domain_scores_codex":[0.998778,0.00009760421,0.0006212,0.0001047564,0.0002717891,0.0001265965],"domain_scores_gemma":[0.9991712,0.00009295584,0.0003596129,0.00006084457,0.0001210386,0.0001943391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2586948,0.001722215,0.03431033,0.00115421,0.0003236042,0.000325583,0.01017097,0.00006057466,0.6658188,0.00005040475,0.000261325,0.02710723],"study_design_scores_gemma":[0.4453408,0.09532496,0.05377049,0.00211945,0.002847066,0.000171526,0.001685619,0.0006919293,0.3967232,0.0001100739,0.0006556575,0.0005592465],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997772,0.00006999197,0.0005462558,0.0009245685,0.0001386089,0.0001817279,0.0000312581,0.00000985269,0.0003256829],"genre_scores_gemma":[0.9974851,0.0006247367,0.0006392229,0.0009845763,0.0001735282,0.00000405963,0.00007163555,0.00001242846,0.000004698536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2690956,"threshold_uncertainty_score":0.3837386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01825069058503744,"score_gpt":0.2959066989232209,"score_spread":0.2776560083381835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}