{"id":"W3038277510","doi":"10.1016/j.jcmgh.2020.06.007","title":"T-Cell Specificity Matters in IBD: Impaired IL10 Production Revealed by OmpC-Tetramers","year":2020,"lang":"en","type":"letter","venue":"Cellular and Molecular Gastroenterology and Hepatology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Children's Hospital","funders":"Crohn's and Colitis Foundation; BC Children's Hospital; Children's Hospital Foundation","keywords":"Immunology; Antigen; Immune system; Acquired immune system; Inflammatory bowel disease; Crohn's disease; Disease; Flagellin; Microbiome; Immunity; Inflammation; Mucosal immunology; Innate immune system; T cell; Biology; Medicine; Bioinformatics; Genetics; Internal medicine; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002735889,0.0004563879,0.000450952,0.0007233288,0.0001332604,0.0004991505,0.0002536026,0.0009106706,0.002879865],"category_scores_gemma":[0.0004266705,0.0001873812,0.0003569659,0.0004473798,0.0003841077,0.0004468096,0.0003290815,0.001542436,0.0009920587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002776826,"about_ca_system_score_gemma":0.0001955641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002385531,"about_ca_topic_score_gemma":0.0002505362,"domain_scores_codex":[0.9997689,0.00005761713,0.00002230088,0.00004316184,0.0000508437,0.0000571765],"domain_scores_gemma":[0.9998369,0.00003134733,0.00004761076,0.00001753464,0.00001805943,0.00004845303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001536681,0.0001755448,0.002307106,0.0005022208,0.00003106556,0.00118002,0.0000834274,0.00008822638,0.9773002,0.0002705792,0.001177179,0.01534779],"study_design_scores_gemma":[0.0006181052,0.004295709,0.1405737,0.0006796176,0.0003667989,0.02310447,0.0006716709,0.002725656,0.7663636,0.004166622,0.05634181,0.00009223131],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"editorial","genre_scores_codex":[0.9170902,0.05852673,0.006861669,0.005649914,0.001042994,0.000134002,0.001677078,0.0004111108,0.008606289],"genre_scores_gemma":[0.9807191,0.01155418,0.002388045,0.001564039,0.0002346894,0.00008876887,0.0009804837,0.00005547444,0.002415284],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.002879865,"threshold_uncertainty_score":0.009634078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004818746047192755,"score_gpt":0.1879660154007287,"score_spread":0.1831472693535359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}