{"id":"W3038301034","doi":"10.3390/molecules25133048","title":"Towards Robust Delivery of Antimicrobial Peptides to Combat Bacterial Resistance","year":2020,"lang":"en","type":"review","venue":"Molecules","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Antimicrobial peptides; Antimicrobial; Computational biology; Antibiotic resistance; Multiple drug resistance; Immune system; Biology; Peptide; Antibiotics; Microbiology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003682191,0.0007125092,0.0007046769,0.001168004,0.0001470645,0.0006963162,0.0004991443,0.0008323459,0.00145096],"category_scores_gemma":[0.0002856129,0.0002660032,0.0003826875,0.0008130888,0.000253509,0.0008553022,0.0005042093,0.001284769,0.001171923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004125778,"about_ca_system_score_gemma":0.0004563414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003096726,"about_ca_topic_score_gemma":0.0004589103,"domain_scores_codex":[0.999845,0.00002547175,0.00001515678,0.00002469409,0.00006345456,0.00002621578],"domain_scores_gemma":[0.9999268,0.00002549065,0.000016532,0.000003201098,0.00001985901,0.000008027831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009703285,0.000160329,0.0001550867,0.02302518,0.00009349125,0.0004926685,0.0001303462,0.001289793,0.07344354,0.01054353,0.01580392,0.874765],"study_design_scores_gemma":[0.00002309093,0.0002829512,0.0005998568,0.00172294,0.00007762347,0.001586341,0.00004610078,0.0003972286,0.01564757,0.001507829,0.9780837,0.00002481007],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001327307,0.9953306,0.001098185,0.0001731253,0.0002212774,0.00001624425,0.00002279258,0.00002143476,0.001789036],"genre_scores_gemma":[0.00433395,0.9930347,0.0008838724,0.0001757424,0.00009847974,0.00002233385,0.00004646338,0.000003726123,0.001400647],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00145096,"threshold_uncertainty_score":0.004853904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0286229679842862,"score_gpt":0.2560434825481113,"score_spread":0.2274205145638251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}