{"id":"W3038389507","doi":"10.1101/2020.07.01.183129","title":"Mechanically stable knot formed by strand threading in Zika virus RNA confers RNase resistance","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Research Council Canada; Canadian Institutes of Health Research; Alberta Innovates","keywords":"Exoribonuclease; Pseudoknot; RNA; RNase P; Knot (papermaking); Biology; Genetics; Materials science; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009748701,0.0001718959,0.0001061723,0.0001087601,0.0001181176,0.000251097,0.0001286255,0.0002419967,0.0006144505],"category_scores_gemma":[0.0001925224,0.0001318017,0.0001815327,0.00005857255,0.0001952531,0.0001363354,0.0001655552,0.0003196269,0.000134687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001745317,"about_ca_system_score_gemma":0.00007637351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003128758,"about_ca_topic_score_gemma":0.000379634,"domain_scores_codex":[0.9999082,0.00001646793,0.000008756776,0.0000162758,0.00002563713,0.00002473195],"domain_scores_gemma":[0.9998822,0.00002766728,0.0000426506,0.00001699212,0.000007592072,0.00002285652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001934961,0.000005156961,0.0002176952,0.000006400657,0.000001980172,0.00003458895,0.0000077434,0.00007854969,0.9993063,0.00008435538,0.000005250285,0.0002325167],"study_design_scores_gemma":[0.0000121069,0.0001937675,0.009566176,0.000003132973,0.000008597517,0.0003338393,0.00002184692,0.003840575,0.9851056,0.0001383094,0.0007697686,0.000006321734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998511,0.00008101772,0.001138529,0.00001306119,0.000004137452,0.000003124793,0.00001776381,0.00002671808,0.00020462],"genre_scores_gemma":[0.9986577,0.00003478002,0.0008759365,0.000005850084,0.000001672588,0.000002670773,0.00004833634,0.000006983408,0.0003660868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006144505,"threshold_uncertainty_score":0.002055585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0136290873480012,"score_gpt":0.2178331382186356,"score_spread":0.2042040508706344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}