{"id":"W3038698704","doi":"10.1016/j.bone.2020.115518","title":"Fifty years of bisphosphonates: What are their mechanical effects on bone?","year":2020,"lang":"en","type":"article","venue":"Bone","topic":"Bone health and osteoporosis research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institutes of Health; Procter and Gamble; Mount Allison University; Merck","keywords":"Osteoporosis; Medicine; Cortical bone; Animal studies; Ovariectomized rat; Bone mass; Animal model; Bone Density Conservation Agents; Bone tissue; Dentistry; Internal medicine; Bone density; Biomedical engineering; Pathology; Estrogen","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002338408,0.000124162,0.0004650433,0.00005671778,0.00003286452,0.00001597666,0.00007792916,0.0001359617,0.0001732618],"category_scores_gemma":[0.0005462025,0.0001012818,0.0001206751,0.000279554,0.00004285304,0.00006731238,0.00006733352,0.0003613324,0.0002873235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003754799,"about_ca_system_score_gemma":0.0001232155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003681027,"about_ca_topic_score_gemma":0.0000111895,"domain_scores_codex":[0.9986403,0.00006407128,0.00024267,0.000277387,0.0004427654,0.0003328193],"domain_scores_gemma":[0.9987861,0.0002794291,0.00008496281,0.0002855695,0.00007711976,0.0004868472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007696865,0.001159486,0.003939006,0.005408969,0.000170608,0.001579844,0.002429541,0.000004662757,0.1525191,0.001086062,0.06201039,0.7619955],"study_design_scores_gemma":[0.01149457,0.008442242,0.1705844,0.00336871,0.0001003292,0.00007680822,0.002109832,0.0009684387,0.6757968,0.0003965359,0.1261315,0.0005298665],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766624,0.004276927,0.00001312793,0.01789175,0.0001606159,0.0006353031,0.00001366849,0.00005976414,0.0002864327],"genre_scores_gemma":[0.9912464,0.000963464,0.0001752612,0.007139963,0.0001218924,0.00002590737,0.00001428206,0.00002922111,0.0002835885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7614656,"threshold_uncertainty_score":0.4130152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03169252832945815,"score_gpt":0.3027377287388982,"score_spread":0.2710452004094401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}