{"id":"W3038734683","doi":"10.1016/j.cytogfr.2020.07.005","title":"Engineering and combining oncolytic measles virus for cancer therapy","year":2020,"lang":"en","type":"review","venue":"Cytokine & Growth Factor Reviews","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario; Ottawa Hospital","funders":"Terry Fox Research Institute; Ontario Institute for Cancer Research","keywords":"Oncolytic virus; Virotherapy; Measles virus; Virology; Measles; Immunotherapy; Virus; Cancer; Biology; Medicine; Vaccination; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004059194,0.0007755529,0.002316354,0.0001145479,0.0000988209,0.00007890163,0.0005633032,0.0003683411,0.00006683965],"category_scores_gemma":[0.0003169868,0.0006041835,0.0007605975,0.0002567334,0.00006295577,0.00000712815,0.0001756945,0.0003840865,0.0000366373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009633006,"about_ca_system_score_gemma":0.0003595763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001263197,"about_ca_topic_score_gemma":0.00002438848,"domain_scores_codex":[0.9973396,0.0002366635,0.0007933749,0.0008989112,0.0002062687,0.0005251686],"domain_scores_gemma":[0.998594,0.00009368459,0.0003761231,0.0005548846,0.0001036388,0.0002776592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001363509,0.00003023672,0.000002858055,0.009434021,0.0003330034,0.000003325044,0.00002384183,4.477625e-7,0.01351,0.000008184189,0.001424985,0.9750928],"study_design_scores_gemma":[0.0006502089,0.001076823,0.000001205392,0.002888422,0.0001828384,0.0000110165,0.000001222116,0.000009668285,0.004161295,0.000002909212,0.9904116,0.0006027581],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003581126,0.9954244,0.0001305827,0.0000522925,0.0001945496,0.003226567,0.0005561979,0.00003227144,0.00002505996],"genre_scores_gemma":[0.00004625511,0.9961062,0.0002019544,0.0002159673,0.0008387812,0.001848747,0.0004190617,0.0002067856,0.0001162117],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9889867,"threshold_uncertainty_score":0.9996409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09590158642665528,"score_gpt":0.3779218080387998,"score_spread":0.2820202216121445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}