{"id":"W3038892567","doi":"10.1159/000507816","title":"Rechallenge Strategy in Cancer Therapy","year":2020,"lang":"en","type":"review","venue":"Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Medicine; Clinical trial; Disease; Immunotherapy; Cancer; Intensive care medicine; Drug; Chemotherapy; Drug resistance; Oncology; Targeted therapy; Limiting; Internal medicine; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004503956,0.0005282522,0.0009041438,0.001616676,0.0002425874,0.0008383233,0.0005702687,0.000828033,0.004238147],"category_scores_gemma":[0.0005297448,0.0001854408,0.0005908301,0.001133868,0.0003553043,0.001082049,0.0005139185,0.001465372,0.001694198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005653853,"about_ca_system_score_gemma":0.0005735885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000537573,"about_ca_topic_score_gemma":0.001275139,"domain_scores_codex":[0.9997942,0.00004669907,0.00002279406,0.00004118302,0.00007070519,0.00002450554],"domain_scores_gemma":[0.9998312,0.00009669627,0.00002513576,0.000005243623,0.00003155188,0.00001005058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008303479,0.0001043949,0.0002091498,0.02022703,0.00009184638,0.0002699821,0.00008652808,0.0007229529,0.004915437,0.007415046,0.01810162,0.9477729],"study_design_scores_gemma":[0.0000151224,0.0001996291,0.0005420227,0.003133015,0.0001060669,0.001471054,0.00004429131,0.0001657773,0.001556505,0.002495463,0.9902546,0.00001649398],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003523572,0.9967159,0.0003669381,0.0002604743,0.0001552565,0.00001349706,0.00003066789,0.00001295499,0.002091955],"genre_scores_gemma":[0.002873281,0.9953586,0.0003492519,0.0002822632,0.0001022415,0.0000168555,0.00005249034,0.000002946366,0.0009619811],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004238147,"threshold_uncertainty_score":0.01417804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2353207309519675,"score_gpt":0.4782777483600704,"score_spread":0.2429570174081029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}