{"id":"W3039285173","doi":"10.3390/cells9071584","title":"Pro-Inflammatory Signaling Upregulates a Neurotoxic Conotoxin-Like Protein Encrypted Within Human Endogenous Retrovirus-K","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Winnipeg","funders":"Canadian Institutes of Health Research; Rare Disease Foundation; Natural Sciences and Engineering Research Council of Canada; Manitoba Medical Service Foundation; Canada Foundation for Innovation; Research Manitoba","keywords":"Biology; Neurodegeneration; Endogenous retrovirus; Cell biology; Pathology; Medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006388644,0.0001726436,0.00007315634,0.000109423,0.00008717311,0.0002051434,0.00005964615,0.000135573,0.001233467],"category_scores_gemma":[0.00009564465,0.00005574664,0.00009714153,0.0001055122,0.0001556737,0.0001032586,0.000114234,0.0001972811,0.0002245816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001808219,"about_ca_system_score_gemma":0.000107565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002259308,"about_ca_topic_score_gemma":0.0003214494,"domain_scores_codex":[0.9999237,0.00001185277,0.000009793883,0.00002185466,0.00001474811,0.00001800347],"domain_scores_gemma":[0.9999361,0.00001063508,0.00002523484,0.000008654067,0.000005490775,0.00001387505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006461427,0.00001415652,0.0004935036,0.00000903297,0.000001951779,0.0001289354,0.00001043156,0.00001913148,0.9988787,0.0000374528,0.000007069999,0.0003351383],"study_design_scores_gemma":[0.00001684138,0.0004378495,0.02687391,0.000005430181,0.00001446904,0.001777097,0.00008777912,0.0006366387,0.9689385,0.00008068475,0.001127775,0.000003143188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989319,0.0001411996,0.0005079149,0.00001356155,0.000003904186,0.000005081845,0.00008182292,0.00001286137,0.0003017367],"genre_scores_gemma":[0.9985091,0.0000932718,0.0004154695,0.00001104624,0.000001804937,0.000004972217,0.0002055789,0.000003855332,0.0007547689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001233467,"threshold_uncertainty_score":0.00412631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04012023686816509,"score_gpt":0.2015384146026354,"score_spread":0.1614181777344703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}