{"id":"W3039382986","doi":"10.1074/jbc.ra120.014555","title":"PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide–dependent biofilm formation","year":2020,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Calgary; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Office of Extramural Research, National Institutes of Health; Alberta Innovates; National Institute of Biomedical Imaging and Bioengineering; Hospital for Sick Children; Canada Foundation for Innovation; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Cystic Fibrosis Canada; Canada Research Chairs; Government of Canada","keywords":"Biofilm; Operon; Gene cluster; Mutant; Gene; Pseudomonas aeruginosa; Biology; Chemistry; Biochemistry; Bacteria; Microbiology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001296408,0.0004793256,0.0003043802,0.0001998269,0.0002201277,0.0003323149,0.0002170842,0.0002414109,0.001888847],"category_scores_gemma":[0.0001621444,0.0001059361,0.0003344051,0.0001738539,0.0002448182,0.0002809772,0.0002106387,0.0004587784,0.0004574951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002427685,"about_ca_system_score_gemma":0.0002303529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001152438,"about_ca_topic_score_gemma":0.0006815097,"domain_scores_codex":[0.9999121,0.00001283308,0.000005265486,0.00002218324,0.00002923523,0.00001835444],"domain_scores_gemma":[0.9999048,0.00002044903,0.00002261284,0.000006871893,0.00001617985,0.00002906976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006058618,0.00001924009,0.000511203,0.00002792412,0.00000624325,0.00004672263,0.00001034412,0.00005551451,0.9978216,0.0001059048,0.00004344426,0.00129135],"study_design_scores_gemma":[0.000002824625,0.0000797008,0.005711029,0.000001832395,0.000009231661,0.000175807,0.00001642398,0.001124397,0.9910464,0.00005251469,0.001775112,0.00000469112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779203,0.001306509,0.01639872,0.0003590943,0.0000564194,0.00003757676,0.00115221,0.000138471,0.002630738],"genre_scores_gemma":[0.9830872,0.0007740148,0.01022307,0.00004613449,0.00001289163,0.00002100592,0.002221322,0.00002328376,0.003591156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001888847,"threshold_uncertainty_score":0.006318808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02805126159768299,"score_gpt":0.2452392128983076,"score_spread":0.2171879513006246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}