{"id":"W3039543009","doi":"10.1161/hypertensionaha.120.14974","title":"Affinity-Enhanced Multimeric VEGF (Vascular Endothelial Growth Factor) and PlGF (Placental Growth Factor) Variants for Specific Adsorption of sFlt-1 to Restore Angiogenic Balance in Preeclampsia","year":2020,"lang":"en","type":"article","venue":"Hypertension","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Placental growth factor; Soluble fms-like tyrosine kinase-1; Preeclampsia; Vascular endothelial growth factor; Growth factor; Angiogenesis; Internal medicine; Medicine; Chemistry; Endocrinology; Andrology; Biology; Pregnancy; Receptor; VEGF receptors","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000152674,0.0002588792,0.0001505569,0.0001090553,0.00006797913,0.0001412977,0.0001673395,0.0001926604,0.0003166053],"category_scores_gemma":[0.0001511063,0.00007804975,0.0002199079,0.00009973477,0.0000838097,0.0001192065,0.0001062742,0.000250177,0.0001212427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002263146,"about_ca_system_score_gemma":0.00009327953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003593152,"about_ca_topic_score_gemma":0.0003338973,"domain_scores_codex":[0.9999061,0.0000234459,0.000007820926,0.00001955272,0.00002637522,0.00001668356],"domain_scores_gemma":[0.9999523,0.000008372727,0.00001747786,0.000004230937,0.000005651548,0.00001193856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006567377,0.00004706756,0.0001525033,0.00001528771,0.000005769647,0.00002364842,0.000008722913,0.0006737634,0.997533,0.00005701507,0.00002504722,0.001392533],"study_design_scores_gemma":[0.00001988851,0.0004856715,0.0009401997,0.000002564583,0.0000159238,0.0001488474,0.000005132407,0.00711413,0.9904271,0.0000255302,0.000810014,0.000005059095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869642,0.0007813755,0.01175921,0.00004512501,0.00001896388,0.00004037476,0.00005064279,0.00005445441,0.0002857191],"genre_scores_gemma":[0.9904908,0.0002977799,0.008622467,0.00002718394,0.000004637179,0.00002069138,0.00008654781,0.00001018264,0.0004397361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003593152,"threshold_uncertainty_score":0.001642048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04137608548822438,"score_gpt":0.2488524013649709,"score_spread":0.2074763158767465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}