{"id":"W3039674172","doi":"10.1101/2020.07.04.187492","title":"Connective-Tissue Growth Factor (CTGF/CCN2) Contributes to TGF-β1-Induced Lung Fibrosis","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; McMaster University; St. Joseph’s Healthcare Hamilton","funders":"","keywords":"CTGF; Extracellular matrix; Fibrosis; Pulmonary fibrosis; Growth factor; Idiopathic pulmonary fibrosis; Connective tissue; Transforming growth factor; Downregulation and upregulation; Myofibroblast; Lung; Pathology; Cancer research; Medicine; Biology; Endocrinology; Internal medicine; Cell biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001895558,0.0005542189,0.0001603099,0.0003171228,0.0002236416,0.0002303356,0.0001273153,0.0003340769,0.001390507],"category_scores_gemma":[0.0001154368,0.0001058543,0.0002409202,0.0001407287,0.0002846585,0.0001347534,0.0001642542,0.0005858785,0.0003217164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003212056,"about_ca_system_score_gemma":0.0002470079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001143012,"about_ca_topic_score_gemma":0.001051195,"domain_scores_codex":[0.99989,0.0000255546,0.0000062333,0.00001787868,0.00003084055,0.00002946974],"domain_scores_gemma":[0.9998958,0.00001035529,0.00002706424,0.000008869197,0.00001343636,0.0000443877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001561391,0.00003195037,0.0004497959,0.00004922754,0.00000468241,0.0001519573,0.00000711314,0.00004297356,0.9980474,0.00008628413,0.00008028342,0.0008923371],"study_design_scores_gemma":[0.0001046026,0.0004338694,0.03008647,0.00003468955,0.00003390879,0.001773286,0.00004865713,0.002828361,0.9571939,0.0001876865,0.007266687,0.000007877322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810191,0.01011936,0.003667809,0.0004573402,0.0001000139,0.00009059712,0.0004350678,0.0001258458,0.003984937],"genre_scores_gemma":[0.9922115,0.002309441,0.00170896,0.0001045877,0.00004178973,0.00006082162,0.0004211141,0.0000105988,0.003131274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001390507,"threshold_uncertainty_score":0.004651725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02216907157548025,"score_gpt":0.2724961515758825,"score_spread":0.2503270800004023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}