{"id":"W3040242669","doi":"10.3390/ijms21134759","title":"Signaling Pathways That Control Muscle Mass","year":2020,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":212,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"H2020 Marie Skłodowska-Curie Actions; Associazione Italiana per la Ricerca sul Cancro; AFM-Téléthon; Agenzia Spaziale Italiana","keywords":"Skeletal muscle; Proteostasis; Muscle atrophy; Biology; Mechanism (biology); Transcription factor; Homeostasis; Bioinformatics; Myokine; Disease; Oxidative stress; Cell biology; Neuroscience; Medicine; Endocrinology; Internal medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004191796,0.0002201156,0.0005266674,0.0001412792,0.00006044913,0.00007494487,0.001288125,0.0001771614,0.00003152404],"category_scores_gemma":[0.0001646512,0.0001690045,0.0006258129,0.0001042948,0.0002085848,0.00001121419,0.00009640115,0.0002262869,0.00001059241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001982211,"about_ca_system_score_gemma":0.0005504422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001591087,"about_ca_topic_score_gemma":4.166394e-7,"domain_scores_codex":[0.9983813,0.0001899779,0.0004547267,0.0002935727,0.0005063472,0.0001740955],"domain_scores_gemma":[0.9988296,0.00004608922,0.0007200653,0.0001155649,0.0001887446,0.00009990322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008305048,0.00008731124,0.00001869584,0.0002936407,0.00115083,0.0004374048,0.00004378717,0.0005246215,0.05177179,0.0006586739,0.0005776875,0.9443525],"study_design_scores_gemma":[0.0004562231,0.0004150681,0.000004655584,0.0008173723,0.0001804488,0.0001524018,0.00006036661,0.00002004719,0.001857218,0.0006455868,0.9951183,0.0002723734],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006765015,0.9894741,0.008187403,0.0001739824,0.0008353048,0.0001071965,0.00002876214,0.000003904199,0.0005129141],"genre_scores_gemma":[0.051571,0.9465958,0.0007478404,0.0005665147,0.0004649918,0.000005548989,0.00002246685,0.00001755245,0.000008282609],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9945406,"threshold_uncertainty_score":0.6891802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03630174661331649,"score_gpt":0.3140236276696152,"score_spread":0.2777218810562987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}