{"id":"W3040242669","doi":"10.3390/ijms21134759","title":"Signaling Pathways That Control Muscle Mass","year":2020,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":212,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"H2020 Marie Skłodowska-Curie Actions; Associazione Italiana per la Ricerca sul Cancro; AFM-Téléthon; Agenzia Spaziale Italiana","keywords":"Skeletal muscle; Proteostasis; Muscle atrophy; Biology; Mechanism (biology); Transcription factor; Homeostasis; Bioinformatics; Myokine; Disease; Oxidative stress; Cell biology; Neuroscience; Medicine; Endocrinology; Internal medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003964848,0.0008868217,0.0008972842,0.001532073,0.000283996,0.001042154,0.000898419,0.001019045,0.004100601],"category_scores_gemma":[0.0004781753,0.0002285904,0.0004304592,0.001038018,0.0004255289,0.001057881,0.0006702607,0.002066769,0.00338745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006716013,"about_ca_system_score_gemma":0.0008556271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00067152,"about_ca_topic_score_gemma":0.001028722,"domain_scores_codex":[0.9998518,0.00002158737,0.00001845985,0.00002986237,0.00005591382,0.00002235238],"domain_scores_gemma":[0.9998827,0.00003632445,0.00001622183,0.000004782393,0.00004331125,0.0000166649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001377495,0.00007747817,0.0002624697,0.01385808,0.0001111335,0.0002833299,0.00008310838,0.0006192295,0.01038151,0.01165529,0.04982437,0.9127063],"study_design_scores_gemma":[0.00001159194,0.00005919798,0.0007721171,0.001600742,0.00005378715,0.0006718868,0.00003618058,0.0000969085,0.001376453,0.002669439,0.9926361,0.00001546122],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002224136,0.9963158,0.0003582017,0.0004929978,0.0005320206,0.000007621447,0.0000511679,0.00002357816,0.001996296],"genre_scores_gemma":[0.000938808,0.9970561,0.0002574121,0.00019046,0.0001732162,0.000009912435,0.00006280657,0.000002381647,0.001308934],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004100601,"threshold_uncertainty_score":0.01371783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03630174661331649,"score_gpt":0.3140236276696152,"score_spread":0.2777218810562987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}