{"id":"W3040408758","doi":"10.1111/1462-2920.15149","title":"Distinct functions of two <scp>FabA</scp> ‐like dehydratase domains of polyunsaturated fatty acid synthase in the biosynthesis of very long‐chain polyunsaturated fatty acids","year":2020,"lang":"en","type":"article","venue":"Environmental Microbiology","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Research Council (Canada); University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Biochemistry; Dehydratase; Biosynthesis; Mutant; ATP synthase; Docosahexaenoic acid; Polyunsaturated fatty acid; Fatty acid; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007894749,0.0002965788,0.0001889927,0.000177339,0.00009861272,0.0003141341,0.0002214966,0.0002411027,0.000450237],"category_scores_gemma":[0.0001050145,0.0001531081,0.0002643016,0.000144866,0.0002102043,0.0002184823,0.0002914642,0.0003309961,0.0002910932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003445745,"about_ca_system_score_gemma":0.0002213423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008522836,"about_ca_topic_score_gemma":0.0007962658,"domain_scores_codex":[0.999917,0.00001060407,0.000009701028,0.00001849343,0.00002109427,0.00002305987],"domain_scores_gemma":[0.9999001,0.00001106792,0.00002511135,0.00001108731,0.00001124998,0.00004142654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008682044,0.000008690788,0.0004224263,0.00001376994,0.000002610909,0.00006222168,0.00001004768,0.00005681289,0.9986753,0.0000978766,0.000009129965,0.000554311],"study_design_scores_gemma":[0.00003206141,0.00009866394,0.02574733,0.000006490578,0.00002078348,0.001042377,0.00007016031,0.00190418,0.9688758,0.0001074419,0.002082661,0.00001200779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978582,0.0004169257,0.001024967,0.00003850991,0.000005970698,0.000006585253,0.0001457429,0.0000155646,0.000487527],"genre_scores_gemma":[0.9973513,0.0001566108,0.0009878326,0.00002680944,0.000002831535,0.00000699994,0.0005588114,0.00000666272,0.0009020672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008522836,"threshold_uncertainty_score":0.002500057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005982055771678615,"score_gpt":0.1935859133602913,"score_spread":0.1876038575886127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}